https://scholars.lib.ntu.edu.tw/handle/123456789/531512
標題: | Common variable immunodeficiency with hypoglycemia, Kikuchi lymphadenitis, and hemiparesis in two siblings | 作者: | YIN-HSIU CHIEN YAO-HSU YANG WUH-LIANG HWU Chou C.-C. BOR-LUEN CHIANG |
公開日期: | 2003 | 卷: | 36 | 期: | 1 | 起(迄)頁: | 65-68 | 來源出版物: | Journal of Microbiology, Immunology and Infection | 摘要: | Common variable immunodeficiency is a heterogeneous group of disorders with arthritis and/or arthralgia as its most commonly associated autoimmune manifestation. We report 2 cases of common variable immunodeficiency in siblings who also had other unusual signs and symptoms. A 10-year-old boy suffered from bradycardia, hypothermia, hypoglycemia, and chronic eczema. His 13-year-old sister suffered from Kikuchi lymphadenitis, hypoperfusion and atrophy of the left cerebral hemisphere, and hemiparesis. They both showed classical laboratory findings of common variable immunodeficiency and the boy's associated symptoms responded to intravenous immunoglobulin therapy. The findings from these cases suggest that a defect in the neuro-endocrine-immune axis may be one of the genetic bases of common variable immunodeficiency. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0037355074&partnerID=40&md5=54f76d8176c7b997d1039efdbe04f2e4 https://scholars.lib.ntu.edu.tw/handle/123456789/531512 |
ISSN: | 0253-2662 | SDG/關鍵字: | immunoglobulin; adolescent; arthralgia; arthritis; article; autoimmune disease; bradycardia; brain atrophy; brain perfusion; case report; child; common variable immunodeficiency; disease association; eczema; female; hemiparesis; human; hypoglycemia; hypothermia; immunotherapy; Kikuchi disease; male; Adolescent; Child; Common Variable Immunodeficiency; Female; Histiocytic Necrotizing Lymphadenitis; Humans; Hypoglycemia; Male; Paresis; Siblings |
顯示於: | 醫學系 |
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