https://scholars.lib.ntu.edu.tw/handle/123456789/531848
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Yang J.-Y. | en_US |
dc.contributor.author | JENQ-WEN HUANG | en_US |
dc.contributor.author | CHIH-KANG CHIANG | en_US |
dc.contributor.author | Pan C.-C. | en_US |
dc.contributor.author | KWAN-DUN WU | en_US |
dc.contributor.author | TUN-JUN TSAI | en_US |
dc.contributor.author | Chen W.-Y. | en_US |
dc.creator | Yang J.-Y.;Jenq-Wen Huang;Chiang C.-K.;Pan C.-C.;Wu K.-D.;Tsai T.-J.;Chen W.-Y. | - |
dc.date.accessioned | 2020-12-24T07:01:42Z | - |
dc.date.available | 2020-12-24T07:01:42Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0931-0509 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-36749097993&doi=10.1093%2fndt%2fgfm231&partnerID=40&md5=030ccf1b43343e65c4890326abba507e | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/531848 | - |
dc.description.abstract | Background. Sleep disorders are prevalent in patients with end-stage renal disease. Increasing evidence suggests that cytokines are involved in the regulation of sleep and wakefulness. The purpose of this study was to examine the relationship between quality of sleep and plasma interleukin-18 levels in peritoneal dialysis patients. Methods. Plasma interleukin-18 levels were determined by the enzyme-linked immunosorbent assay (ELISA) methodology in 57 peritoneal dialysis patients. Quality of sleep was measured using the Pittsburgh Sleep Quality Index. Demographic and routine laboratory data were recorded. Results. In our cohort, the poor sleepers had higher plasma interleukin-18 levels (559.16 ± 261.22 pg/ml vs 397.49 ± 191.81 pg/ml, P = 0.01). The plasma interleukin-18 level was positively correlated with the Pittsburgh Sleep Quality Index score (r = 0.286, P = 0.031), that is, there was a positive association between higher plasma interleukin-18 levels and poorer quality of sleep. Conclusion. This study demonstrates that interleukin-18 may be involved in sleep disorders in end-stage renal disease patients. Higher plasma interleukin-18 levels are associated with poorer quality of sleep in peritoneal dialysis patients. Whether a cause-and-effect relationship exists between interleukin-18 and quality of sleep deserves further study. ? The Author [2007]. Published by Oxford University Press on behalf of ERA-EDTA. All rights reserved. | en_US |
dc.relation.ispartof | Nephrology Dialysis Transplantation | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | interleukin 18; adult; article; controlled study; demography; enzyme linked immunosorbent assay; female; human; major clinical study; male; peritoneal dialysis; Pittsburgh Sleep Quality Index; priority journal; protein blood level; scoring system; sleep; sleep pattern; Adult; Female; Humans; Interleukin-18; Male; Middle Aged; Peritoneal Dialysis; Quality of Life; Sleep | - |
dc.title | Higher plasma interleukin-18 levels associated with poor quality of sleep in peritoneal dialysis patients | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1093/ndt/gfm231 | - |
dc.identifier.pmid | 17890740 | - |
dc.identifier.scopus | 2-s2.0-36749097993 | - |
dc.relation.pages | 3606-3609 | en_US |
dc.relation.journalvolume | 22 | en_US |
dc.relation.journalissue | 12 | en_US |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Toxicology | - |
crisitem.author.dept | Integrated Diagnostics and Therapeutics-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Institute of Food Safety and Health | - |
crisitem.author.dept | Center for Biotechnology | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-8011-2317 | - |
crisitem.author.orcid | 0000-0001-9021-4616 | - |
crisitem.author.orcid | 0000-0002-3339-1509 | - |
crisitem.author.orcid | 0000-0002-1666-8940 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | Others: University-Level Research Centers | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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