https://scholars.lib.ntu.edu.tw/handle/123456789/532348
標題: | In vitro study of peritoneal fibrosis | 作者: | KUAN-YU HUNG KWAN-DUN WU TUN-JUN TSAI |
公開日期: | 2007 | 卷: | 27 | 期: | SUPPL. 2 | 起(迄)頁: | S72-S75 | 來源出版物: | Peritoneal Dialysis International | 摘要: | Peritoneal fibrosis (PF) is an important issue in peritoneal dialysis (PD) because it remains one of the reading causes of patient drop-out from PD. In this review, we focus on in vitro approaches to the pathogenesis and therapeutic potential of PF and on associated clinical implications. Representative Asian studies, initiated since mid-1990s, that have investigated matrix accumulation in peritoneal tissue possibly leading to PF in the PD population will be highlighted as examples to learn how to apply this research tool. As compared with data from well-designed clinical trials, observations from in vitro models may be far from becoming solid evidence; however, they do cast new light on options for investigations into therapeutic pharmaceuticals. Copyright ? 2007 International Society for Peritoneal Dialysis. Printed in Canada. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-35748972973&partnerID=40&md5=ead0b0f6239820cac4fb0600d5da5dec https://scholars.lib.ntu.edu.tw/handle/123456789/532348 |
ISSN: | 0896-8608 | SDG/關鍵字: | cytokine; growth factor; tamoxifen; Asia; conference paper; data analysis; fibroblast; fibrosis; human; in vitro study; pathogenesis; peritoneal disease; polymorphonuclear cell; priority journal; Animals; Apoptosis; Dialysis Solutions; Epithelial Cells; Fibrosis; Humans; Inflammation Mediators; Kidney Failure, Chronic; Peritoneal Dialysis; Peritoneum |
顯示於: | 醫學系 |
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