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  1. NTU Scholars
  2. 理學院
  3. 數學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/533286
DC FieldValueLanguage
dc.contributor.authorLin, Y.-J.en_US
dc.contributor.authorLin, H.-C.en_US
dc.contributor.authorYang, Y.-F.en_US
dc.contributor.authorChen, C.-Y.en_US
dc.contributor.authorLing, M.-P.en_US
dc.contributor.authorChen, S.-C.en_US
dc.contributor.authorChen, W.-Y.en_US
dc.contributor.authorYou, S.-H.en_US
dc.contributor.authorLu, T.-H.en_US
dc.contributor.authorYI-FAN YANGen_US
dc.contributor.authorCHUNG-MIN LIAOen_US
dc.creatorLin, Y.-J.;Lin, H.-C.;Yang, Y.-F.;Chen, C.-Y.;Ling, M.-P.;Chen, S.-C.;Chen, W.-Y.;You, S.-H.;Lu, T.-H.;Liao, C.-M.-
dc.date.accessioned2020-12-25T09:42:47Z-
dc.date.available2020-12-25T09:42:47Z-
dc.date.issued2019-
dc.identifier.urihttps://www.scopus.com/inward/record.url?eid=2-s2.0-85076595915&partnerID=40&md5=713ff4bbd168c54113cfc1bec2e8c20f-
dc.identifier.urihttps://scholars.lib.ntu.edu.tw/handle/123456789/533286-
dc.description.abstractBackground: Broad-scale evidence has shown the significant association between ambient air pollutants and the development of tuberculosis (TB). However, the impact of air quality on the risk of TB in Taiwan is still poorly understood. Objective: To develop a probabilistic integrated population-level risk assessment approach for evaluating the contribution of ambient air pollution exposure to the risk of TB development among different regions of Taiwan. Materials and methods: A Bayesian-based probabilistic risk assessment model was implemented to link exposure concentrations of various air pollutants quantified in a probabilistic manner with the population-based exposure-response models developed by using an epidemiological investigation. Results: The increment of the risk of TB occurred in a region with a higher level of air pollution, indicating a strong relationship between ambient air pollution exposures and TB incidences. Carbon monoxide (CO) exposure showed the highest population attributable fraction (PAF), followed by nitrogen oxides (NOX) and nitrogen dioxide (NO2) exposures. In a region with higher ambient air pollution, it is most likely (80% risk probability) that the contributions of CO exposure to development of TB were 1.6–12.2% (range of median PAFs), whereas NOX and NO2 exposures contributed 1.2–9.8% to developing TB. Conclusion: Our findings provide strong empirical support for the hypothesis and observations from the literature that poor air quality is highly likely to link aetiologically to the risk of TB. Therefore, substantial reductions in CO, NOX, and NO2 exposures are predicted to have health benefits to susceptible and latently infected individuals that provide complementary mitigation efforts in reducing the burden of TB. Considering that people continue to be exposed to both TB bacilli and ambient air pollutants, our approach can be applied for different countries/regions to identify which air pollutants contribute to a higher risk of TB in order to develop potential mitigation programs. ? 2019 Lin et al.-
dc.relation.ispartofInfection and Drug Resistance-
dc.subject.othercarbon monoxide; nitrogen dioxide; nitrogen oxide; air pollutant; air pollution; air quality; ambient air; Article; concentration (parameter); disease predisposition; dose response; exposure; geographic distribution; incidence; particulate matter; prediction; risk; risk assessment; simulation; Taiwan; tuberculosis-
dc.subject.other[SDGs]SDG3-
dc.titleAssociation between ambient air pollution and elevated risk of tuberculosis developmenten_US
dc.typejournal article-
dc.identifier.doi10.2147/IDR.S227823-
dc.identifier.pmid31827330-
dc.identifier.scopus2-s2.0-85076595915-
dc.relation.pages3835-3847-
dc.relation.journalvolume12-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.openairetypejournal article-
item.fulltextno fulltext-
item.cerifentitytypePublications-
crisitem.author.deptMathematics-
crisitem.author.deptBioenvironmental Systems Engineering-
crisitem.author.orcid0000-0002-8360-7996-
crisitem.author.parentorgCollege of Science-
crisitem.author.parentorgCollege of Bioresources and Agriculture-
Appears in Collections:數學系
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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
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開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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