Cytomegalovirus retinitis and immune recovery uveitis in AIDS patients treated with highly active antiretroviral therapy in Taiwanese
Journal
Ocular Immunology and Inflammation
Journal Volume
16
Journal Issue
3
Pages
83-87
Date Issued
2008
Author(s)
Lin Y.-C.
Chen M.-Y.
Abstract
Purpose: To determine the characteristics of cytomegalovirus (CMV) retinitis and immune recovery uveitis (IRU) in the era of highly active antiretroviral therapy (HAART). Methods: We reviewed data from 47 of 79 consecutive patients with acquired immunodeficiency syndrome (AIDS) and CMV retinitis. Results: The incidence of CMV retinitis in AIDS patients has markedly decreased over the recent 10 years. The characteristics of CMV retinitis have changed. Development of IRU occurred in 24.4%. Conclusions: Symptomatic IRU develops in a significant number of patients with inactive CMV retinitis following successful HAART. Eyes with IRU respond favorably to antiinflammatory therapy without reactivation of retinitis. Copyright ? Informa Healthcare USA, Inc.
SDGs
Other Subjects
antiretrovirus agent; ganciclovir; triamcinolone; acquired immune deficiency syndrome; adult; article; controlled study; Cytomegalovirus; female; highly active antiretroviral therapy; human; immune reconstitution inflammatory syndrome; major clinical study; male; ophthalmoscopy; retina macula edema; retinitis; uveitis; virus reactivation; visual acuity; Acquired Immunodeficiency Syndrome; Adult; Antiretroviral Therapy, Highly Active; Cytomegalovirus Retinitis; Female; Humans; Immune System; Incidence; Male; Middle Aged; Recovery of Function; Retrospective Studies; Taiwan; Uveitis
Type
journal article