https://scholars.lib.ntu.edu.tw/handle/123456789/536660
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | LIAN-YU LIN | en_US |
dc.contributor.author | Kuo H.-K. | en_US |
dc.contributor.author | HWANG, JUEY-JEN | en_US |
dc.contributor.author | LING-PING LAI | en_US |
dc.contributor.author | FU-TIEN CHIANG | en_US |
dc.contributor.author | Tseng C.-D. | en_US |
dc.contributor.author | JIUNN-LEE LIN | en_US |
dc.date.accessioned | 2020-12-31T02:57:18Z | - |
dc.date.available | 2020-12-31T02:57:18Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-62749195623&doi=10.1016%2fj.atherosclerosis.2008.07.021&partnerID=40&md5=166ee82e02eefc41321edfe03b823b91 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/536660 | - |
dc.description.abstract | Objective: Bilirubin is a potent antioxidant and a cyroprotectant. Low serum bilirubin is associated with atherosclerosis. Little is known about its role in metabolic syndrome (MS) among children and adolescents. Methods: We examined 4723 children and adolescents aged 12-17 years with reliable measures of various serum hepatic profiles and metabolic risks from Health and Nutrition Examination Survey 1999-2004. Results: The results showed that the prevalence of the MS was from 6.6 ± 1.2% in the lowest quartile to 2.1 ± 1.9% in the highest quartile of the concentration of total bilirubin. The graded association remained significant after the adjustment of other co-variates. The odds ratios for the MS were around 0.29 (0.08-0.99) and 0.23 (0.08-0.65) for the upper two quartiles when using the lowest quartile as reference for the concentration of total bilirubin. The quartiles of the serum total bilirubin levels were inversely correlated with the homeostasis model assessment (HOMA-IR) and insulin while not associated with the serum C-reactive protein (CRP) levels. Conclusions: The serum total bilirubin levels are inversely correlated with the prevalence of the MS. The mechanism of the association between MS and total bilirubin may be related to the insulin resistance status. ? 2008 Elsevier Ireland Ltd. All rights reserved. | - |
dc.relation.ispartof | Atherosclerosis | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | bilirubin; insulin; adolescent; article; bilirubin blood level; child; clinical feature; controlled study; disease association; disease marker; female; groups by age; health survey; homeostasis; human; insulin resistance; major clinical study; male; metabolic syndrome X; prevalence; priority journal; protein blood level; reliability; school child; Adolescent; Antioxidants; Bilirubin; C-Reactive Protein; Child; Cohort Studies; Cross-Sectional Studies; Female; Humans; Inflammation; Insulin Resistance; Male; Metabolic Syndrome X; Odds Ratio; Prevalence | - |
dc.title | Serum bilirubin is inversely associated with insulin resistance and metabolic syndrome among children and adolescents | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.atherosclerosis.2008.07.021 | - |
dc.identifier.pmid | 18775539 | - |
dc.identifier.scopus | 2-s2.0-62749195623 | - |
dc.relation.pages | 563-568 | - |
dc.relation.journalvolume | 203 | - |
dc.relation.journalissue | 2 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Master's Program in Smart Medicine and Health Informatics (SMARTMHI) | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-7505-6429 | - |
crisitem.author.orcid | 0000-0001-6437-0455 | - |
crisitem.author.orcid | 0000-0002-9651-7420 | - |
crisitem.author.orcid | 0000-0003-4936-8968 | - |
crisitem.author.orcid | 0000-0003-2148-3956 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | International College | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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