https://scholars.lib.ntu.edu.tw/handle/123456789/536740
標題: | Cardiac rhythm disturbances in patients with left atrial isomerism | 作者: | MEI-HWAN WU JOU-KOU WANG JIUNN-LEE LIN LING-PING LAI HUNG-CHI LUE FON-JOU HSIEH |
公開日期: | 2001 | 出版社: | Futura Publishing Company Inc. | 卷: | 24 | 期: | 11 | 起(迄)頁: | 1631-1638 | 來源出版物: | PACE - Pacing and Clinical Electrophysiology | 摘要: | This long-term study sought to determine the clinical implication of defective sinus node and A V conduction tissue in patients with left atrial isomerism (LAI). From 1984 to 1998, a total of 22 patients were identified as LAI. Patient age at the last follow-up ranged from 2 to 276 months (90 ± 70 months). Associated cardiac anomalies were interruption of the inferior vend cava (n = 18, 82%), common atrium (n = 9, 41%), AV canal (n = 14, 64%), double-outlet right ventricle (n = 8, 36%), and pulmonary stenosis (n = 15, 68%). Palliative interventions were performed in 16 patients (Fontan-type operation in 4 patients, shunt followed by Fontan-type operation in 2, repair of septal defect in 4, and extracardiac intervention in 6). During the follow-up, over half of the patients (n = 14, 64%) developed bradyarrhythmia (onset age: from i to 264 months; median 78 months): junctional rhythm (n = 11), sinus bradycardia (n = 8) (5 patients also had junctional rhythm), and A V block (n = 2, both also had junctional rhythm). The probability free from bradyarrhythmia was 80% and 46% at the age of 2 and 6 years, respectively. None of the bradyarrhythmias were directly related to open-heart surgery. Besides, junctional ectopic tachycardia occurred after Fontan-type operation in three of six patients. In two patients, a Mahaim-like pathway was identified during the electrophysiological study. The patients with LAI had a high probability of developing bradyarrhythmias clue to abnormal sinus node function. Varied A V conduction abnormalities may include compromised A V conduction, junctional ectopic tachycardia after Fontan-type operation, and an association of Mahaim-like pathway. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0035165432&doi=10.1046%2fj.1460-9592.2001.01631.x&partnerID=40&md5=8ee117bf8c2c35de4812c17acefb1b38 https://scholars.lib.ntu.edu.tw/handle/123456789/536740 |
ISSN: | 0147-8389 | DOI: | 10.1046/j.1460-9592.2001.01631.x | SDG/關鍵字: | adolescent; adult; article; atrioventricular block; atrioventricular conduction; bradycardia; child; clinical article; congenital heart disease; female; follow up; Fontan procedure; heart arrhythmia; heart electrophysiology; heart left right shunt; heart right ventricle double outlet; heart septum defect; human; infant; male; open heart surgery; pulmonary valve stenosis; shunting; sinus node dysfunction |
顯示於: | 醫學系 |
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