https://scholars.lib.ntu.edu.tw/handle/123456789/537007
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lien T.-H. | en_US |
dc.contributor.author | MEI-HWEI CHANG | en_US |
dc.contributor.author | JIA-FENG WU | en_US |
dc.contributor.author | HUEY-LING CHEN | en_US |
dc.contributor.author | Lee H.-C. | en_US |
dc.contributor.author | Chen A.-C. | en_US |
dc.contributor.author | Tiao M.-M. | en_US |
dc.contributor.author | Wu T.-C. | en_US |
dc.contributor.author | Yang Y.-J. | en_US |
dc.contributor.author | Lin C.-C. | en_US |
dc.contributor.author | Lai M.-W. | en_US |
dc.contributor.author | HONG-YUAN HSU | en_US |
dc.contributor.author | YEN-HSUAN NI | en_US |
dc.creator | Lien T.-H.;Mei-Hwei Chang;Wu J.-F.;Chen H.-L.;Lee H.-C.;Chen A.-C.;Tiao M.-M.;Wu T.-C.;Yang Y.-J.;Lin C.-C.;Lai M.-W.;Hsu H.-Y.;Ni Y.-H. | - |
dc.date.accessioned | 2021-01-04T07:33:52Z | - |
dc.date.available | 2021-01-04T07:33:52Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0270-9139 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-78751505016&doi=10.1002%2fhep.24023&partnerID=40&md5=c7f8e9793415599838b9666ef9302386 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/537007 | - |
dc.description.abstract | In Taiwan, a screening system using an infant stool color card to promote the early diagnosis of biliary atresia (BA) was established in 2002. This study aimed to investigate the 5-year outcome of BA before and after using the screening program. BA patients were divided into three cohorts according to their birth dates. The patients in cohort A (n = 89) were born before the stool card screening program (1990-2000); those in cohort B (n = 28) were screened by the stool card regional screening program (2002-2003); and those in cohort C (n = 74) were screened by the stool card universal screening program (2004-2005). The relative odds ratios were computed using logistic regression to compare the different factors affecting survival time. The rate of age at Kasai operation <60 days was 49.4% and 65.7% in cohorts A and B+C, respectively (P = 0.02). The jaundice-free (total serum bilirubin <2.0 mg/dL) rate 3 months after surgery was 34.8% and 60.8% in cohorts A and B+C, respectively (P < 0.001). The 3-year jaundice-free survival rate with native liver was 31.5% in cohort A and 56.9% in cohort B+C (P < 0.001), whereas the 3-year overall survival rates were 64.0% and 89.2%, respectively (P < 0.001). The 5-year jaundice-free survival rate with native liver was 27.3% in cohort A and 64.3% in cohort B (P < 0.001), and the 5-year overall survival rates were 55.7% and 89.3%, respectively (P < 0.001). Conclusion: The stool color card screening program for BA allows for earlier Kasai operation, which increases the jaundice-free rate at 3 months postsurgery. With higher surgical success rates, the 3- and 5-year outcome of BA patients in Taiwan improves remarkably. ? 2010 American Association for the Study of Liver Diseases. | - |
dc.relation.ispartof | Hepatology | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | bilirubin; article; bile duct atresia; bilirubin blood level; cohort analysis; color; disease free survival; feces analysis; female; human; infant; infant stool color card; jaundice; major clinical study; male; newborn; outcome assessment; overall survival; portoenterostomy; priority journal; risk assessment; screening; survival time; Taiwan; Biliary Atresia; Cohort Studies; Color; Disease-Free Survival; Feces; Female; Humans; Infant; Infant, Newborn; Male; Neonatal Screening; Portoenterostomy, Hepatic; Treatment Outcome | - |
dc.title | Effects of the infant stool color card screening program on 5-year outcome of biliary Atresia in Taiwan | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1002/hep.24023 | - |
dc.identifier.pmid | 21140377 | - |
dc.identifier.scopus | 2-s2.0-78751505016 | - |
dc.relation.pages | 202-208 | - |
dc.relation.journalvolume | 53 | - |
dc.relation.journalissue | 1 | - |
item.cerifentitytype | Publications | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.orcid | 0000-0002-3648-9261 | - |
crisitem.author.orcid | 0000-0001-6343-1658 | - |
crisitem.author.orcid | 0000-0002-4074-5838 | - |
crisitem.author.orcid | 0000-0002-5720-4835 | - |
crisitem.author.orcid | 0000-0002-1158-5249 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。