https://scholars.lib.ntu.edu.tw/handle/123456789/537062
標題: | Pancreaticobiliary anomalies is the leading cause of childhood recurrent pancreatitis | 作者: | Su W.-J. HUEY-LING CHEN HONG-SHIEE LAI YEN-HSUAN NI MEI-HWEI CHANG |
公開日期: | 2007 | 出版社: | Scientific Communications International Ltd | 卷: | 106 | 期: | 2 | 起(迄)頁: | 119-125 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Background/purpose: To explore the etiology, age and gender distribution, complications, and prognosis of recurrent pediatric pancreatitis. Methods: Between 1993 and 2005, 92 children were hospitalized at the National Taiwan University Hospital with pancreatitis. Only 25 diagnosed with recurrent pancreatitis, based on two or more episodes of pancreatitis, elevated serum amylase and/or lipase levels ? 3 times the upper limit of normal, radiographic evidence, and clinical symptoms, were enrolled. Results: A total of 85 episodes of pancreatitis in 25 patients (16 girls, 9 boys; mean age, 9.5±4.4 years; 3.4±1.9 episodes per person) were documented. The recurrence rate of pediatric pancreatitis was 27.2%. Recurrent pancreatitis was associated with pancreaticobiliary structural anomalies (n = 7), biliary stones or sludge (n = 4), hyperlipidemia (n = 3), pseudopapillary tumor of the pancreas (n = 2), trauma (n = 2), hypoxic encephalopathy with recurrent bacteremia and sepsis (n = 1), and idiopathic (n = 6). The age and gender distribution according to etiologies were not different (p = 0.301 for age, p = 0.137 for gender). Complications included cholangitis or cholestasis (16%), pancreatic necrosis (16%), pseudocyst formation (12%), shock (8%), hemorrhagic pancreatitis (4%), and diabetes mellitus (4%). No patient died of recurrent pancreatitis. Long-term morbidity after recurrent pancreatitis presented as gout, diabetes mellitus, non-alcoholic steatohepatitis, and chronic pancreatitis. Conclusion: For children who suffer from recurrent pancreatitis, pancreaticobiliary structural anomalies should be considered first. ? 2007 Elsevier & Formosan Medical Association. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33847777682&doi=10.1016%2fS0929-6646%2809%2960227-8&partnerID=40&md5=db6e0eef506a88896883eed22c1273c4 https://scholars.lib.ntu.edu.tw/handle/123456789/537062 |
ISSN: | 0929-6646 | DOI: | 10.1016/S0929-6646(09)60227-8 | SDG/關鍵字: | amylase; triacylglycerol lipase; age distribution; amylase blood level; article; bacteremia; biliary tract malformation; brain hypoxia; child; cholestasis; chronic pancreatitis; clinical article; clinical feature; diabetes mellitus; female; gallstone; gout; hemorrhagic pancreatitis; hepatobiliary radiography; human; hyperlipidemia; injury; male; morbidity; nonalcoholic fatty liver; normal value; pancreas malformation; pancreas necrosis; pancreas pseudocyst; pancreatitis; pseudotumor; recurrence risk; recurrent infection; sepsis; shock; Taiwan; triacylglycerol lipase blood level; university hospital |
顯示於: | 醫學系 |
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