https://scholars.lib.ntu.edu.tw/handle/123456789/537130
Title: | Serum γ-glutamyl transpeptidase activity and bile acids in normal Taiwanese infants | Authors: | Huang Y.-C. HUEY-LING CHEN KEH-SUNG TSAI Tang J.-R. YEN-HSUAN NI MEI-HWEI CHANG |
Issue Date: | 2002 | Journal Volume: | 43 | Journal Issue: | 5 | Start page/Pages: | 245-248 | Source: | Acta Paediatrica Taiwanica | Abstract: | To facilitate making a diagnosis of cholestatic liver disease in Taiwan, we have established reference ranges for serum γ-glutamyl transpeptidase (γ-GT) activity and bile acids in normal Taiwanese infants. The serum level of γ-GT activity was assayed in 90 normal Taiwanese infants and children aged between 2 days and 2 years old. These data were analyzed in twenty-three 0-3-month-old, twenty-four 4-6-month-old, and forty-three 7-24-month-old infants. The mean values of serum γ-GT activity were 47.4±26.6, 21.5±7.3, and 14.0±3.2 1U/L for the respective age groups. The highest reference γ-GT values were 99.5, 35.8, and 20.3 1U/L for the respective age groups. The mean values of serum γ-GT activity were highest in infants younger than 3 months, and these gradually decreased to the adult level with age (p < 0.01). Serum bile acids were measured in 24 premature and 56 full-term infants. The mean values of serum bile acids were 34.5±34.5 μmol/L in preterm infants and 18.7±21.9 μmol/L in full-term babies. The bile acid levels of preterm infants were higher than those in full-term babies (p < 0.01). |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036762902&partnerID=40&md5=09b879fbe1a0a2bd2e0525aa512399fb https://scholars.lib.ntu.edu.tw/handle/123456789/537130 |
ISSN: | 1608-8115 | SDG/Keyword: | bile acid; gamma glutamyltransferase; article; bile acid blood level; differential diagnosis; enzyme activity; gamma glutamyl transferase blood level; human; infant; intrahepatic cholestasis; newborn; normal human; prematurity; Taiwan; Bile Acids and Salts; gamma-Glutamyltransferase; Humans; Infant, Newborn; Reference Values; Taiwan |
Appears in Collections: | 醫學系 |
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