https://scholars.lib.ntu.edu.tw/handle/123456789/537169
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lin W.-T. | en_US |
dc.contributor.author | Lin S.-J. | en_US |
dc.contributor.author | YEN-HSUAN NI | en_US |
dc.contributor.author | HUEY-LING CHEN | en_US |
dc.contributor.author | HSIU-PO WANG | en_US |
dc.contributor.author | Chu J.-S. | en_US |
dc.contributor.author | MEI-HWEI CHANG | en_US |
dc.creator | Lin W.-T.;Lin S.-J.;Ni Y.-H.;Chen H.-L.;Wang H.-P.;Chu J.-S.;Mei-Hwei Chang | - |
dc.date.accessioned | 2021-01-04T07:38:44Z | - |
dc.date.available | 2021-01-04T07:38:44Z | - |
dc.date.issued | 1999 | - |
dc.identifier.issn | 0929-6646 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0032984837&partnerID=40&md5=b254db89c3946dee45d3b794fb5a62ee | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/537169 | - |
dc.description.abstract | Primary sclerosing cholangitis (PSC) is a rare disease in Taiwan and has not been described in Taiwanese children previously. We report a 4-year-old girl who presented with prolonged fever, eosinophilia (11%), hepatomegaly, and markedly elevated serum levels of alkaline phosphatase (3,318 IU/L) and γ-glutamyl transpeptidase (475 IU/L). Subsequent investigations including endoscopic retrograde cholangiopancreatography and liver histology confirmed the diagnosis of PSC. Treatment with a low dose of prednisolone for 2 months and ursodeoxycholic acid during 32 months of follow-up resulted in clinical remission and halted disease progression. A high index of suspicion is necessary for physicians to diagnose this disorder in children with chronic liver disease. Our experience in this case indicates that therapy with prednisolone and ursodeoxycholic acid may be helpful for the treatment of PSC in children, and suggests the need for more trials of combined therapy. | en_US |
dc.relation.ispartof | Journal of the Formosan Medical Association | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | prednisolone; ursodeoxycholic acid; article; case report; chronic liver disease; clinical feature; disease course; endoscopic retrograde cholangiopancreatography; eosinophilia; female; human; preschool child; remission; sclerosing cholangitis; Taiwan; Age of Onset; Child, Preschool; Cholagogues and Choleretics; Cholangiopancreatography, Endoscopic Retrograde; Cholangitis, Sclerosing; Eosinophilia; Female; Humans; Liver; Taiwan; Ursodeoxycholic Acid | - |
dc.title | Primary sclerosing cholangitis in a child | en_US |
dc.type | journal article | en |
dc.identifier.pmid | 10365542 | - |
dc.identifier.scopus | 2-s2.0-0032984837 | - |
dc.relation.pages | 209-213 | en_US |
dc.relation.journalvolume | 98 | en_US |
dc.relation.journalissue | 3 | en_US |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.orcid | 0000-0002-1158-5249 | - |
crisitem.author.orcid | 0000-0002-4074-5838 | - |
crisitem.author.orcid | 0000-0002-7741-9315 | - |
crisitem.author.orcid | 0000-0002-3648-9261 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。