https://scholars.lib.ntu.edu.tw/handle/123456789/537482
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Lan T.-Y. | en_US |
dc.contributor.author | Lin D.-T. | en_US |
dc.contributor.author | HWEI-FANG TIEN | en_US |
dc.contributor.author | RONG-SEN YANG | en_US |
dc.contributor.author | Chen C.-Y. | en_US |
dc.contributor.author | Wu K. | en_US |
dc.date.accessioned | 2021-01-04T12:12:49Z | - |
dc.date.available | 2021-01-04T12:12:49Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0001-5792 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-70350557176&doi=10.1159%2f000253592&partnerID=40&md5=f12981d42bbc01621c5f5b25b9ef4b81 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/537482 | - |
dc.description.abstract | Purpose: To investigate the possible prognostic factors of survival outcomes in patients with granulocytic sarcoma (GS). Methods: We retrospectively investigated the prognostic factors determining survival in 24 patients with GS using Kaplan-Meier survival analysis followed by log rank tests. We evaluated gender, age, location, GS antedating leukemia, underlying disorders, treatment type and stem cell transplantation. Results: The 5-year survival rate for the patients with GS was 21%. The patients undergoing chemotherapy had a significantly longer survival time compared to those who did not (p = 0.0009). We found no difference in the 5-year survival rate among the patients undergoing chemotherapy combined with radiation or surgery. Patients with chronic myelogenous leukemia and myelodysplastic disorders had worse survival rates (p = 0.0028). Conclusion: Early diagnosis with biopsy and early chemotherapy can improve survival outcome. Local radiation or surgery can improve symptoms but does not influence survival outcomes. ? 2009 S. Karger AG, Basel. | - |
dc.relation.ispartof | Acta Haematologica | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | cyclophosphamide; cytarabine; idarubicin; adolescent; adult; age distribution; aged; allogeneic hematopoietic stem cell transplantation; article; cancer chemotherapy; cancer diagnosis; cancer localization; cancer radiotherapy; cancer surgery; cancer survival; cause of death; child; chronic myeloid leukemia; clinical article; controlled study; cytogenetics; diagnostic imaging; female; follow up; granulocytic sarcoma; histopathology; human; male; medical record review; myelodysplastic syndrome; onset age; preschool child; priority journal; prognosis; school child; sex difference; stem cell transplantation; survival rate; treatment outcome; Adolescent; Adult; Aged; Antineoplastic Agents; Child; Child, Preschool; Combined Modality Therapy; Female; Humans; Kaplan-Meier Estimate; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid, Acute; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Retrospective Studies; Sarcoma, Myeloid; Translocation, Genetic; Treatment Outcome; Young Adult | - |
dc.title | Prognostic factors of treatment outcomes in patients with granulocytic sarcoma | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1159/000253592 | - |
dc.identifier.pmid | 19887783 | - |
dc.identifier.scopus | 2-s2.0-70350557176 | - |
dc.relation.pages | 238-246 | - |
dc.relation.journalvolume | 122 | - |
dc.relation.journalissue | 4 | - |
item.openairetype | journal article | - |
item.fulltext | no fulltext | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Orthopedic Surgery-NTUH | - |
crisitem.author.dept | Orthopedic Surgery | - |
crisitem.author.orcid | 0000-0002-1384-5593 | - |
crisitem.author.orcid | 0000-0002-0553-4779 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。