https://scholars.lib.ntu.edu.tw/handle/123456789/537570
標題: | Severe aplastic anemia induced by ticlopidine: Report of a case | 作者: | Su C.-C. Tseng C.-D. HWANG, JUEY-JEN HWEI-FANG TIEN Lee Y.-T. |
公開日期: | 1995 | 卷: | 94 | 期: | 11 | 起(迄)頁: | 689-691 | 來源出版物: | Journal of the Formosan Medical Association | 摘要: | Ticlopidine is a powerful antiplatelet activator that inhibits adenosine diphosphate (ADP)-induced platelet aggregation. Its most common side-effects are skin rashes, diarrhea and neutropenia. Aplastic anemia is rare. This paper reports a patient with severe aplastic anemia that developed after the use of ticlopidine. The 85-year-old woman developed fever, chills and chest pain 5 weeks after starting ticlopidine 250 mg twice daily. Severe aplastic anemia was proved by blood examination, bone marrow aspiration and biopsy. In spite of the recovery of absolute neutrophil count to more than 1,000/mm3, 16 days after ticlopidine was stopped and administration of strong antibiotics, the patient died from candidal sepsis. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0028871911&partnerID=40&md5=0a259c57def4190b341303bfde116da6 https://scholars.lib.ntu.edu.tw/handle/123456789/537570 |
ISSN: | 0929-6646 | SDG/關鍵字: | ticlopidine; aged; aplastic anemia; article; case report; diarrhea; female; human; neutropenia; rash; Aged; Aged, 80 and over; Anemia, Aplastic; Case Report; Female; Human; Platelet Aggregation Inhibitors; Ticlopidine |
顯示於: | 醫學系 |
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