https://scholars.lib.ntu.edu.tw/handle/123456789/539686
標題: | Local massage after vaccination enhances the immunogenicity of diphtheria-tetanus-pertussis vaccine | 作者: | Hsu C.-Y. LI-MIN HUANG Lee C.-Y. Lin T.-Y. PING-ING LEE JONG-MIN CHEN |
公開日期: | 1995 | 卷: | 14 | 期: | 7 | 起(迄)頁: | 567-572 | 來源出版物: | Pediatric Infectious Disease Journal | 摘要: | The effect of local massage on adverse reactions and immunogenicity of diphtheria-tetanus-pertussis vaccine was investigated. After diphtheria-tetanus-pertussis vaccination 327 infants were either massaged or not, and adverse reactions were evaluated. Local pain and fever were more frequent in the massage group. The extra febrile episodes from massage were mild (38–39°C). For evaluation of the antibody responses, 124 infants were recruited into massage or nonmassage cohorts and antibody production was measured at 2, 6, 7, 18 and 19 months of age, respectively. Subjects in the massage group developed significantly higher antibodies against filamentous hemagglutinin at 6 and 7 months of age, pertussis toxin at 6, 7, 18 and 19 months of age, pertussis agglutinogen at 18 and 19 months of age and diphtheria toxoid at 6 and 7 months of age than those in the nonmassage group. Local massage after diphtheria-tetanus-pertussis vaccination was associated with better immunogenicity and more adverse reactions, including low grade fever and local pain, which were mild and not particularly disturbing. ? 1995 by Williams and Wilkins. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-0029025417&doi=10.1097%2f00006454-199507000-00003&partnerID=40&md5=d1d66e62fa394da9299f0f4d7891a058 https://scholars.lib.ntu.edu.tw/handle/123456789/539686 |
ISSN: | 0891-3668 | DOI: | 10.1097/00006454-199507000-00003 | SDG/關鍵字: | diphtheria pertussis tetanus vaccine; antibody response; article; diphtheria; human; immunization; immunogenicity; infant; major clinical study; massage; pertussis; priority journal; tetanus; Antibodies, Bacterial; Comparative Study; Diphtheria; Diphtheria-Tetanus-Pertussis Vaccine; Drug Administration Schedule; Female; Human; Infant; Male; Massage; Support, Non-U.S. Gov't; Tetanus; Vaccination; Whooping Cough |
顯示於: | 醫學系 |
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