https://scholars.lib.ntu.edu.tw/handle/123456789/540792
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | CHYI-FENG JAN | en_US |
dc.contributor.author | Chen C.-J. | en_US |
dc.contributor.author | Chiu Y.-H. | en_US |
dc.contributor.author | Chen L.-S. | en_US |
dc.contributor.author | Wu H.-M. | en_US |
dc.contributor.author | Huang C.-C. | en_US |
dc.contributor.author | Yen M.-F. | en_US |
dc.contributor.author | Chen, Tony Hsiu Hsi | en_US |
dc.creator | Chyi-Feng Jan;Chen C.-J.;Chiu Y.-H.;Chen L.-S.;Wu H.-M.;Huang C.-C.;Yen M.-F.;Chen T.H.-H. | - |
dc.date.accessioned | 2021-01-14T06:26:00Z | - |
dc.date.available | 2021-01-14T06:26:00Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0307-0565 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-33646367660&doi=10.1038%2fsj.ijo.0803204&partnerID=40&md5=edc0adc62e78194b7ca03055105deac4 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/540792 | - |
dc.description.abstract | Objectives: We aimed to assess the association between metabolic syndrome (MS) and hepatitis B/C virus infection using a large population-based study. Design and methods: A population-based cross-sectional study design was adopted with a total of 53 528 subjects being enrolled from the integrated multiple diseases screening program in Keelung, Taiwan. Evidence of past hepatitis B/C infection, acquired during childhood or as a young adult, was identified during the two-stage liver cancer screening part of the process. Information on biochemical markers and anthropometric measures related to MS, such as fasting blood sugar, triglyceride and high-density lipoprotein (HDL), abdominal circumference and blood pressure (BP), were collected routinely while screening for hypertension, type 2 diabetes, and hyperlipidemia. Logistic regression was used to estimate odds ratios and related 95% confidence intervals for the associations between MS and hepatitis B/C infection. Results: High blood pressure (SBP ? 135 mmHg or DBP ? 85 mmHg) (adjusted odd ratio: 0.89 (0.83-0.94)) and high triglyceride (? 150 mg/dl) (adjusted odds ratio: 0.65 (0.60-0.69)) were, after adjusting for gender and age, inversely associated with being HBsAg positive (P < 0.05). The likelihood of developing MS was lower in the HBsAg positive than the HBsAg negative (adjusted odds ratio: 0.84 (0.76-0.93)). A positive association between being anti-HCV positive and having low serum HDL (male < 40 mg/dl, female < 50 mg/dl) was also noted (adjusted odds ratio: 1.61 (1.37-1.88) after controlling for gender and age). High triglyceride was inversely associated with being anti-HCV positive (adjusted odds ratio: 0.63 (0.55-0.71). Conclusions: There is an inverse association between MS and hepatitis B virus infection whereas the association was heterogeneous for HCV infection with a positive association with abnormal serum HDL but an inverse association with hypertriglyceridemia. ? 2006 Nature Publishing Group All rights reserved. | - |
dc.relation.ispartof | International Journal of Obesity | - |
dc.subject | Hepatitis B; Hepatitis C; Metabolic syndrome; Screening | - |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | biochemical marker; glucose; hepatitis B surface antigen; high density lipoprotein; triacylglycerol; abdomen; adult; age; aged; anthropometry; article; blood pressure; cancer staging; controlled study; disease association; female; gender; glucose blood level; hepatitis B; hepatitis C; human; hyperlipidemia; hypertension; hypertriglyceridemia; lipoprotein blood level; liver cancer; major clinical study; male; metabolic syndrome X; non insulin dependent diabetes mellitus; population research; priority journal; screening; Taiwan; triacylglycerol blood level; Adult; Aged; Epidemiologic Methods; Female; Hepacivirus; Hepatitis B; Hepatitis B Surface Antigens; Hepatitis B virus; Hepatitis C; Hepatitis, Chronic; Humans; Male; Metabolic Syndrome X; Middle Aged; Taiwan; Hepatitis B virus; Hepatitis C virus | - |
dc.title | A population-based study investigating the association between metabolic syndrome and Hepatitis B/C infection (Keelung Community-based Integrated Screening Study No. 10) | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1038/sj.ijo.0803204 | - |
dc.identifier.pmid | 16404404 | - |
dc.identifier.scopus | 2-s2.0-33646367660 | - |
dc.relation.pages | 794-799 | - |
dc.relation.journalvolume | 30 | - |
dc.relation.journalissue | 5 | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Family Medicine-NTUH | - |
crisitem.author.dept | Family Medicine | - |
crisitem.author.dept | Referral Management Center | - |
crisitem.author.dept | Institute of Health Data Analytics and Statistics | - |
crisitem.author.dept | Public Health | - |
crisitem.author.orcid | 0000-0003-2893-2187 | - |
crisitem.author.orcid | 0000-0002-5799-6705 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
顯示於: | 醫學系 |
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