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  1. NTU Scholars
  2. 醫學院
  3. 醫學系
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/545372
DC FieldValueLanguage
dc.contributor.authorLiou J.-M.en-US
dc.contributor.authorMalfertheiner P.en-US
dc.contributor.authorLee Y.-C.en-US
dc.contributor.authorSheu B.-S.en-US
dc.contributor.authorSugano K.en-US
dc.contributor.authorCheng H.-C.en-US
dc.contributor.authorYeoh K.-G.en-US
dc.contributor.authorHsu P.-I.en-US
dc.contributor.authorGoh K.-L.en-US
dc.contributor.authorMahachai V.en-US
dc.contributor.authorGotoda T.en-US
dc.contributor.authorChang W.-L.en-US
dc.contributor.authorChen M.-J.en-US
dc.contributor.authorTSUNG-HSIEN CHIANGen-US
dc.contributor.authorChen C.-C.en-US
dc.contributor.authorWu C.-Y.en-US
dc.contributor.authorLeow A.H.-R.en-US
dc.contributor.authorWu J.-Y.en-US
dc.contributor.authorWu D.-C.en-US
dc.contributor.authorHong T.-C.en-US
dc.contributor.authorLu H.en-US
dc.contributor.authorYamaoka Y.en-US
dc.contributor.authorMegraud F.en-US
dc.contributor.authorChan F.K.L.en-US
dc.contributor.authorSung J.J.Y.en-US
dc.contributor.authorLin J.-T.en-US
dc.contributor.authorGraham D.Y.en-US
dc.contributor.authorWu M.-S.en-US
dc.contributor.authorEl-Omar E.M.en-US
dc.date.accessioned2021-02-02T03:08:06Z-
dc.date.available2021-02-02T03:08:06Z-
dc.date.issued2020-
dc.identifier.issn0017-5749-
dc.identifier.urihttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85091493329&doi=10.1136%2fgutjnl-2020-322368&partnerID=40&md5=ac515e72f98d7e2e6ff15831111c71e2-
dc.identifier.urihttps://scholars.lib.ntu.edu.tw/handle/123456789/545372-
dc.description.abstractObjective A global consensus meeting was held to review current evidence and knowledge gaps and propose collaborative studies on population-wide screening and eradication of Helicobacter pylori for prevention of gastric cancer (GC). Methods 28 experts from 11 countries reviewed the evidence and modified the statements using the Delphi method, with consensus level predefined as ?80% of agreement on each statement. The Grading of Recommendation Assessment, Development and Evaluation (GRADE) approach was followed. Results Consensus was reached in 26 statements. At an individual level, eradication of H. pylori reduces the risk of GC in asymptomatic subjects and is recommended unless there are competing considerations. In cohorts of vulnerable subjects (eg, first-degree relatives of patients with GC), a screen-and-treat strategy is also beneficial. H. pylori eradication in patients with early GC after curative endoscopic resection reduces the risk of metachronous cancer and calls for a re-examination on the hypothesis of a € the point of no return'. At the general population level, the strategy of screen-and-treat for H. pylori infection is most cost-effective in young adults in regions with a high incidence of GC and is recommended preferably before the development of atrophic gastritis and intestinal metaplasia. However, such a strategy may still be effective in people aged over 50, and may be integrated or included into national healthcare priorities, such as colorectal cancer screening programmes, to optimise the resources. Reliable locally effective regimens based on the principles of antibiotic stewardship are recommended. Subjects at higher risk of GC, such as those with advanced gastric atrophy or intestinal metaplasia, should receive surveillance endoscopy after eradication of H. pylori. Conclusion Evidence supports the proposal that eradication therapy should be offered to all individuals infected with H. pylori. Vulnerable subjects should be tested, and treated if the test is positive. Mass screening and eradication of H. pylori should be considered in populations at higher risk of GC. ? 2020 BMJ Publishing Group. All rights reserved.-
dc.publisherBMJ Publishing Group-
dc.relation.ispartofGut-
dc.subject.otherantibiotic agent; antiinfective agent; proton pump inhibitor; antimicrobial stewardship; asymptomatic disease; atrophic gastritis; bacterial clearance; cancer incidence; cancer prevention; cancer risk; cancer screening; colorectal cancer; consensus; cost effectiveness analysis; Delphi study; endoscopic surgery; first-degree relative; gastroscopy; Helicobacter infection; high risk patient; human; intestine metaplasia; medical expert; nonhuman; priority journal; Review; risk reduction; screening; stomach atrophy; stomach cancer; Taiwan; vulnerable population; antibiotic resistance; atrophic gastritis; clinical decision making; consensus development; cost benefit analysis; dose response; drug administration; early cancer diagnosis; gastroesophageal reflux; gastrointestinal endoscopy; genetic marker; global health; Helicobacter infection; Helicobacter pylori; intestine flora; metabolic syndrome X; metaplasia; microbiology; reinfection; stomach tumor; Anti-Bacterial Agents; Antimicrobial Stewardship; Clinical Decision-Making; Cost-Benefit Analysis; Delphi Technique; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Resistance, Bacterial; Early Detection of Cancer; Endoscopy, Gastrointestinal; Gastritis, Atrophic; Gastroesophageal Reflux; Gastrointestinal Microbiome; Genetic Markers; Global Health; Helicobacter Infections; Helicobacter pylori; Humans; Metabolic Syndrome; Metaplasia; Proton Pump Inhibitors; Reinfection; Stomach Neoplasms-
dc.subject.other[SDGs]SDG3-
dc.titleScreening and eradication of Helicobacter pylori for gastric cancer prevention: The Taipei global consensusen_US
dc.typereview-
dc.identifier.doi10.1136/gutjnl-2020-322368-
dc.identifier.pmid33004546-
dc.identifier.scopus2-s2.0-85091493329-
dc.relation.pages2093-2112-
dc.relation.journalvolume69-
dc.relation.journalissue12-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.fulltextno fulltext-
item.openairetypereview-
crisitem.author.deptInternal Medicine-NTUH-
crisitem.author.orcid0000-0003-1308-9756-
crisitem.author.parentorgNational Taiwan University Hospital-
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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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