https://scholars.lib.ntu.edu.tw/handle/123456789/545825
標題: | Increased risk of peptic ulcers following a cholecystectomy for gallstones | 作者: | Tsai M.-C. Huang C.-C. Kao L.-T. Lin H.-C. Lee, Cha-Ze |
公開日期: | 2016 | 出版社: | Nature Publishing Group | 卷: | 6 | 來源出版物: | Scientific Reports | 摘要: | This retrospective cohort study examined the relationship between a cholecystectomy and the subsequent risk of peptic ulcers using a population-based database. Data for this study were retrieved from the Taiwan Longitudinal Health Insurance Database 2005. This study included 5209 patients who had undergone a cholecystectomy for gallstones and 15,627 sex- and age-matched comparison patients. We individually tracked each patient for a 5-year period to identify those who subsequently received a diagnosis of peptic ulcers. We found that of the 20,836 sampled patients, 2033 patients (9.76%) received a diagnosis of peptic ulcers during the 5-year follow-up period: 674 from the study group (12.94% of the patients who underwent a cholecystectomy) and 1359 from the comparison group (8.70% of the comparison patients). The stratified Cox proportional hazard regressions showed that the adjusted hazard ratio (HR) for peptic ulcers during the 5-year follow-up period was 1.48 (95% CI = 1.34?1.64) for patients who underwent a cholecystectomy than comparison patients. Furthermore, the adjusted HRs of gastric ulcers and duodenal ulcers during the 5-year follow-up period were 1.70 and 1.71, respectively, for patients who underwent a cholecystectomy compared to comparison patients. This study demonstrated a relationship between a cholecystectomy and a subsequent diagnosis of peptic ulcers. ? The Author(s) 2016. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84982665570&doi=10.1038%2fsrep30702&partnerID=40&md5=87588b1675a11f80af5813f0004921df https://scholars.lib.ntu.edu.tw/handle/123456789/545825 |
ISSN: | 2045-2322 | DOI: | 10.1038/srep30702 | SDG/關鍵字: | adolescent; adult; aged; cholecystectomy; female; gallstone; human; incidence; longitudinal study; male; middle aged; peptic ulcer; retrospective study; risk assessment; Taiwan; very elderly; young adult; Adolescent; Adult; Aged; Aged, 80 and over; Cholecystectomy; Female; Gallstones; Humans; Incidence; Longitudinal Studies; Male; Middle Aged; Peptic Ulcer; Retrospective Studies; Risk Assessment; Taiwan; Young Adult |
顯示於: | 醫學系 |
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