https://scholars.lib.ntu.edu.tw/handle/123456789/547848
標題: | Pulmonary embolism due to protein S deficiency in pregnancy | 作者: | Mak P.-H. MING-KWANG SHYU CHIEN-NAN LEE FON-JOU HSIEH |
公開日期: | 2005 | 出版社: | Elsevier (Singapore) Pte Ltd | 卷: | 44 | 期: | 3 | 起(迄)頁: | 294-296 | 來源出版物: | Taiwanese Journal of Obstetrics and Gynecology | 摘要: | Objective: Inherited thrombophilia is an uncommon disease that may cause recurrent thrombosis and may complicate pregnancy. A patient with protein S deficiency suffered antepartum deep venous thrombosis (DVT) and antepartum pulmonary embolism (PE) in the following pregnancy. She had both successful pregnancies managed by anticoagulant and close fetal surveillance. Case Report: A 28-year-old woman with protein S deficiency experienced an episode of DVT of the left lower extremity in her first pregnancy and an episode of PE in her second pregnancy. In both pregnancies, the venous thromboembolism (VTE) was treated successfully with low-molecular-weight heparin (LMWH). Conclusion: Prophylactic anticoagulant therapy should be administered throughout the antepartum and postpartum periods for pregnant women with inherited thrombophilia and a previously documented VTE. LMWH is the first-line drug of choice for both prophylaxis and treatment of VTE since it does not cross the placenta and is not teratogenic. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-25144433870&doi=10.1016%2fS1028-4559%2809%2960160-1&partnerID=40&md5=cb66dbb7c82d31fc386308c5c8ad2bd9 https://scholars.lib.ntu.edu.tw/handle/123456789/547848 |
ISSN: | 1028-4559 | DOI: | 10.1016/S1028-4559(09)60160-1 | SDG/關鍵字: | low molecular weight heparin; nadroparin; protein S; adult; article; case report; clinical examination; deep vein thrombosis; echography; female; human; laboratory test; leg thrombosis; lung embolism; nuclear magnetic resonance imaging; pregnancy complication; protein S deficiency; puerperium; thrombophilia; vaginal delivery; venous thromboembolism |
顯示於: | 醫學系 |
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