https://scholars.lib.ntu.edu.tw/handle/123456789/550948
標題: | Recurrent cytomegalovirus colitis with megacolon in an immunocompetent elderly man | 作者: | Lin, Yi-Hsuan Yeh, Chi-Ju Chen, Ying-Jen MING-CHU CHANG Su, I-Hao Cheng, Hao-Tsai |
關鍵字: | inclusion body; ganciclovir; Parkinson's disease; toxic megacolon; TOXIC MEGACOLON; ULCERATIVE-COLITIS; GASTROINTESTINAL DYSFUNCTION; PARKINSONS-DISEASE; INFECTION; PATIENT; CELLS | 公開日期: | 四月-2010 | 出版社: | WILEY | 卷: | 82 | 期: | 4 | 起(迄)頁: | 638 | 來源出版物: | Journal of medical virology | 摘要: | Gastrointestinal infection with cytomegalovirus (CMV) is uncommon in immunocompetent hosts. The case of a 70-year-old male with CMV colitis, who has no history of chronic inflammatory bowel disease or immunodeficiency is described. Diagnosis was aided by the identification of inclusion bodies that reacted positively for CMV by immunohistochemical testing in biopsy specimens from the colonic mucosa. His hospital course was characterized by poor improvement of his symptoms after the CMV infection was treated with ganciclovir, and the occurrence of megacolon. A repeat colonoscopy with biopsy revealed a recurrence of the CMV infection. Although CMV colitis is common in immunocompromised patients, we believe this is the first case of CMV colitis with megacolon and recurrent CMV infection in an immunocompetent patient. Colitis caused by CMV colitis should be considered in elderly people with diarrhea. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/550948 | ISSN: | 01466615 | DOI: | 10.1002/jmv.21712 | SDG/關鍵字: | cefuroxime; ganciclovir; metronidazole; abdominal distension; aged; article; case report; cell inclusion; colitis; colon biopsy; colon mucosa; colonoscopy; computer assisted tomography; diarrhea; enteritis; histopathology; human; Human cytomegalovirus; human tissue; immune deficiency; immunocompetence; immunohistochemistry; loose feces; male; megacolon; physical examination; radiodiagnosis; recurrent disease; serology; urinary tract infection; Aged; Antiviral Agents; Colitis; Cytomegalovirus; Cytomegalovirus Infections; Ganciclovir; Humans; Immunohistochemistry; Inclusion Bodies, Viral; Intestinal Mucosa; Male; Megacolon; Recurrence; Treatment Outcome; Cytomegalovirus |
顯示於: | 醫學系 |
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