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  1. NTU Scholars
  2. 醫學院
  3. 醫學院附設醫院 (臺大醫院)
Please use this identifier to cite or link to this item: https://scholars.lib.ntu.edu.tw/handle/123456789/553694
DC FieldValueLanguage
dc.contributor.authorChien S.-C.en-US
dc.contributor.authorChen C.-Y.en-US
dc.contributor.authorLeu H.-B.en-US
dc.contributor.authorSu C.-H.en-US
dc.contributor.authorYin W.-H.en-US
dc.contributor.authorTseng W.-K.en-US
dc.contributor.authorYEN-WEN WUen-US
dc.contributor.authorLin T.-H.en-US
dc.contributor.authorChang K.-C.en-US
dc.contributor.authorWang J.-H.en-US
dc.contributor.authorWu C.-C.en-US
dc.contributor.authorYeh H.-I.en-US
dc.contributor.authorChen J.-W.en-US
dc.date.accessioned2021-03-18T08:54:17Z-
dc.date.available2021-03-18T08:54:17Z-
dc.date.issued2017-
dc.identifier.issn0167-5273-
dc.identifier.urihttps://scholars.lib.ntu.edu.tw/handle/123456789/553694-
dc.description.abstractObjective Coronary heart disease (CHD) is a leading cause of death in developed countries. Exploration of indicators to identify high risk individuals who develop adverse outcomes despite stable baseline condition is important. This study is to evaluate the association between serum albumin concentration and cardiovascular (CV) outcomes in individuals of stable CHD. Methods Seven-hundred–thirty-four participants from Biosignature study, a nationwide prospective cohort study aimed to identity risk factors among patients with stable CHD, were enrolled for analysis. They were divided into low serum albumin group (baseline albumin concentration <?3.5?g/dL, n?=?98) and normal albumin group (baseline albumin concentration ??3.5?g/dL, n?=?636). The relations between baseline albumin and adverse CV outcomes within 18?months of follow-up were analyzed. Results Compared baseline characteristics with normal albumin group, subjects in low albumin group are older, having more diabetic patients, lower hemoglobin level, lower estimated glomerular filtration rate, lower total cholesterol level, lower left ventricular ejection fraction, and higher blood glucose. While there is no significant difference of total CV events between two groups, low serum albumin concentration is associated with an increased risk of all-cause mortality (10.2% vs. 0.5%, p?<?0.001) and hard CV events (7.1% vs. 1.4%, p?<?0.001). The association remains significant after adjustments for confounders (all-cause mortality, HR: 6.81, 95% CI: 1.01–45.62; hard CV events, HR: 3.68, 95% CI: 1.03–13.19). Conclusions Low serum albumin concentration (<?3.5?g/dL) worsens prognosis of patients with stable CHD. ? 2017 Elsevier Ireland Ltd-
dc.relation.ispartofInternational Journal of Cardiology-
dc.subject.otheralbumin; cholesterol; glucose; hemoglobin; biological marker; serum albumin; adult; adverse outcome; age; aged; albumin blood level; Article; cardiovascular disease; cardiovascular risk; cause of death; cholesterol blood level; cohort analysis; controlled study; diabetic patient; disease association; estimated glomerular filtration rate; female; follow up; glucose blood level; heart left ventricle ejection fraction; hemoglobin blood level; high risk patient; human; ischemic heart disease; major clinical study; male; mortality rate; priority journal; prognosis; prospective study; risk assessment; blood; clinical trial; coronary artery disease; diagnostic imaging; metabolism; middle aged; multicenter study; risk factor; Taiwan; very elderly; Aged; Aged, 80 and over; Biomarkers; Cohort Studies; Coronary Disease; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prospective Studies; Risk Factors; Serum Albumin; Taiwan-
dc.subject.other[SDGs]SDG3-
dc.titleAssociation of low serum albumin concentration and adverse cardiovascular events in stable coronary heart diseaseen_US
dc.typejournal article-
dc.identifier.doi10.1016/j.ijcard.2017.04.003-
dc.identifier.pmid28413113-
dc.identifier.scopus2-s2.0-85017453199-
dc.relation.pages1-5-
dc.relation.journalvolume241-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.openairecristypehttp://purl.org/coar/resource_type/c_6501-
item.openairetypejournal article-
item.fulltextno fulltext-
crisitem.author.deptNuclear Medicine-NTUH-
crisitem.author.orcid0000-0003-1520-1166-
crisitem.author.parentorgNational Taiwan University Hospital-
Appears in Collections:醫學院附設醫院 (臺大醫院)
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臺大位居世界頂尖大學之列,為永久珍藏及向國際展現本校豐碩的研究成果及學術能量,圖書館整合機構典藏(NTUR)與學術庫(AH)不同功能平台,成為臺大學術典藏NTU scholars。期能整合研究能量、促進交流合作、保存學術產出、推廣研究成果。

To permanently archive and promote researcher profiles and scholarly works, Library integrates the services of “NTU Repository” with “Academic Hub” to form NTU Scholars.

總館學科館員 (Main Library)
醫學圖書館學科館員 (Medical Library)
社會科學院辜振甫紀念圖書館學科館員 (Social Sciences Library)

開放取用是從使用者角度提升資訊取用性的社會運動,應用在學術研究上是透過將研究著作公開供使用者自由取閱,以促進學術傳播及因應期刊訂購費用逐年攀升。同時可加速研究發展、提升研究影響力,NTU Scholars即為本校的開放取用典藏(OA Archive)平台。(點選深入了解OA)

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