https://scholars.lib.ntu.edu.tw/handle/123456789/557505
Title: | Hepatitis B- and C-related hepatocellular carcinomas yield different clinical features and prognosis | Authors: | CHIEN-HUNG CHEN GUAN-TARN HUANG PEI-MING YANG PEI-JER CHEN Lai M.-Y. DING-SHINN CHEN Wang J.-D. JIN-CHUAN SHEU |
Issue Date: | 2006 | Publisher: | Elsevier Ltd | Journal Volume: | 42 | Journal Issue: | 15 | Start page/Pages: | 2524-2529 | Source: | European Journal of Cancer | Abstract: | The purpose of this study was to compare the clinical features and survival in patients with hepatitis B virus-related hepatocellular carcinoma (HBV-HCC) and hepatitis C virus-related hepatocellular carcinoma (HCV-HCC). A total of 2820 HCC patients were included. The mean age of HBV-HCC patients was 52.5 ± 13.4 years, while it was 64.8 ± 8.7 years in HCV-HCC patients. The male/female ratio was 7.8 in HBV-HCC, while it was 1.7 in HCV-HCC. The mean α-fetoprotein level in HBV-HCC was 11,661 ± 22,805 ng/mL, while it was 5079 ± 15,005 ng/mL in HCV-HCC. The mean tumour size was 6.4 ± 4.1 cm in HBV-HCC, while it was 4.6 ± 3.1 cm in HCV-HCC. The median survival was 11.1 months in HBV-HCC, while it was 23.9 months in HCV-HCC. Compared with HBV-HCC patients, HCV-HCC patients were older, had a lower male/female ratio, lower white blood cell count, lower serum albumin level, higher serum ALT level, lower serum α-fetoprotein level, smaller tumour size and survived longer. ? 2006 Elsevier Ltd. All rights reserved. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-84983719238&doi=10.1016%2fj.ejca.2006.06.007&partnerID=40&md5=6183ec3f368f45f7667e37620683d15f https://scholars.lib.ntu.edu.tw/handle/123456789/557505 |
ISSN: | 0959-8049 | DOI: | 10.1016/j.ejca.2006.06.007 | SDG/Keyword: | alanine aminotransferase; albumin; alcohol; alpha fetoprotein; antiinfective agent; adult; aged; alanine aminotransferase blood level; article; cancer patient; cancer survival; clinical feature; disease association; female; hepatitis B; hepatitis C; human; leukocyte; liver cell carcinoma; major clinical study; male; priority journal; prognosis; tumor volume |
Appears in Collections: | 醫學系 |
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