https://scholars.lib.ntu.edu.tw/handle/123456789/560060
標題: | Effect of simultaneous kidney transplantation on heart-transplantation outcome in recipients with preoperative renal dysfunction | 作者: | RON-BIN HSU CHUNG-I CHANG MENG-KUN TSAI PO-HUANG LEE NAI-KUAN CHOU NAI-HSIN CHI SHOEI-SHEN WANG Chu S.-H. |
公開日期: | 2010 | 卷: | 37 | 期: | 1 | 起(迄)頁: | 68-73 | 來源出版物: | European Journal of Cardio-thoracic Surgery | 摘要: | Objective: There are no guidelines to select isolated heart transplantation or simultaneous heart and kidney transplantation in patients with renal dysfunction. We sought to assess the effect of simultaneous kidney transplantation on heart-transplantation outcome in patients with renal dysfunction. Methods: Retrospective case review. Results: Between 1993 and 2006, 45 patients with preoperative serum creatinine ?2 mg dl-1 underwent heart transplantation, including 32 isolated heart transplantation and 13 simultaneous heart and kidney transplantation. The survival of 83.3 ± 10.8% at 30 days, 58.3 ± 14.2% at 1 year and 50.0 ± 14.4% at 3 years in simultaneous heart and kidney transplantation did not differ from the survival of 81.8 ± 6.7% at 30 days, 66.7 ± 8.2% at 1 year and 45.1 ± 9.3% at 3 years in isolated heart transplantation. The dialysis-free and patient survival of 66.7 ± 13.6% at 30 days, 58.3 ± 14.2% at 1 year and 50.0 ± 14.4% at 3 years in simultaneous heart and kidney transplantation also did not differ from the rate of 81.8 ± 6.7% at 30 days, 66.7 ± 8.2% at 1 year and 31.4 ± 8.9% at 3 years in isolated heart transplantation. Conclusions: Simultaneous kidney transplantation is an effective therapy for patients depending on dialysis pretransplant, reducing postoperative risk of mortality in these very sick patients to the level of patients with less severe renal disease not requiring dialysis before transplant. ? 2009 European Association for Cardio-Thoracic Surgery. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-72749106846&doi=10.1016%2fj.ejcts.2009.06.006&partnerID=40&md5=a237b8b8d2f490ace40d2f77ea2fff66 https://scholars.lib.ntu.edu.tw/handle/123456789/560060 |
ISSN: | 1010-7940 | DOI: | 10.1016/j.ejcts.2009.06.006 | SDG/關鍵字: | creatinine; adolescent; adult; aged; article; clinical article; creatinine blood level; female; heart transplantation; human; kidney dysfunction; kidney transplantation; male; priority journal; renal replacement therapy; survival rate; treatment outcome; Adolescent; Adult; Aged; Child; Epidemiologic Methods; Female; Graft Survival; Heart Failure; Heart Transplantation; Humans; Immunosuppression; Kidney Failure, Chronic; Kidney Transplantation; Male; Middle Aged; Postoperative Care; Renal Dialysis; Treatment Outcome; Young Adult |
顯示於: | 醫學系 |
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