https://scholars.lib.ntu.edu.tw/handle/123456789/560085
Title: | Heart transplantation in patients with extreme right ventricular failure | Authors: | RON-BIN HSU Lin F.-Y. NAI-KUAN CHOU Ko W.-J. NAI-HSIN CHI SHOEI-SHEN WANG |
Issue Date: | 2007 | Journal Volume: | 32 | Journal Issue: | 3 | Start page/Pages: | 457-461 | Source: | European Journal of Cardio-thoracic Surgery | Abstract: | Objective: Donor shortage and improved medical treatment of heart failure increase the prevalence of patients with extreme right ventricular failure and ascites to heart transplantation. The clinical outcome of heart transplantation in these patients has rarely been reported. Here, we sought to evaluate the clinical outcome of heart transplantation in patients with extreme right ventricular failure and refractory ascites. Methods: Data were collected by retrospective chart review. Results: Between 1993 and 2005, 12 patients with extreme right ventricular failure and refractory ascites underwent orthotopic heart transplantation at the authors' hospital. The causes of heart failure were congenital heart disease in four patients, dilated cardiomyopathy in two patients, rheumatic heart disease in two patients, coronary artery disease in two patients, and restrictive cardiomyopathy and transplant coronary artery disease each in one patient. Eight of 12 patients had previous cardiac operation. The findings of preoperative abdominal sonography were massive ascites in all patients, congestive liver in 11 patients, and probably cardiac cirrhosis in 1 patient. One patient underwent combined heart and kidney transplantations. There were six in-hospital deaths: bleeding in three patients and multiple organ failure in three patients. Major postoperative complications occurred in 10 patients: renal failure requiring dialysis in 9, bleeding requiring reoperation in 8 patients. Patients with previous cardiac operation had a higher mortality rate (5/7 vs 1/5). Conclusions: Heart transplantation in patients with extreme right ventricular failure and refractory ascites was associated with high mortality and morbidity. The presence of previous cardiac operation implied even poor prognosis. ? 2007 European Association for Cardio-Thoracic Surgery. |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-34547674712&doi=10.1016%2fj.ejcts.2007.05.015&partnerID=40&md5=5b2e86a12629099b70ccc92b3fab4c8a https://scholars.lib.ntu.edu.tw/handle/123456789/560085 |
ISSN: | 1010-7940 | DOI: | 10.1016/j.ejcts.2007.05.015 | SDG/Keyword: | azathioprine; cyclosporin; mycophenolic acid 2 morpholinoethyl ester; prednisone; tacrolimus; thymocyte antibody; adolescent; adult; article; ascites; bleeding; cardiac cirrhosis; cardiac graft rejection; clinical article; combination chemotherapy; congenital heart disease; congestive cardiomyopathy; controlled study; coronary artery disease; dose response; drug dose reduction; echography; female; heart disease; heart failure; heart hemodynamics; heart right ventricle failure; heart transplantation; human; kidney failure; kidney transplantation; liver congestion; male; medical record; multiple organ failure; orthotopic transplantation; outcome assessment; pathophysiology; postoperative complication; preoperative evaluation; priority journal; restrictive cardiomyopathy; rheumatic heart disease; surgical mortality; treatment outcome; unspecified side effect; Adolescent; Adult; Child; Female; Heart Failure; Heart Transplantation; Humans; Male; Middle Aged; Postoperative Complications; Retrospective Studies; Survival Rate; Treatment Outcome; Ventricular Dysfunction, Right |
Appears in Collections: | 醫學系 |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.