https://scholars.lib.ntu.edu.tw/handle/123456789/560608
Title: | Value of blood culture time to positivity in identifying complicated nontyphoidal Salmonella bacteremia | Authors: | Shang-Yu Chen Weng T.-H. WEN-PIN TSENG CHIA-MING FU Lin H.-W. Liao C.-H. Lee T.-F. PO-REN HSUEH CHENG-CHUNG FANG SHEY-YING CHEN |
Issue Date: | 2018 | Journal Volume: | 91 | Journal Issue: | 3 | Start page/Pages: | 210-216 | Source: | Diagnostic Microbiology and Infectious Disease | Abstract: | Few studies analyzed the association between blood culture time to positivity (TTP) and risk of complicated nontyphoidal Salmonella (NTS) bacteremia. We conducted a retrospective study of 206 patients (aged 60.4 ± 17.4 years) with NTS bacteremia during a 30-month period. Complicated NTS bacteremia was defined as the presence of 30-day mortality, complicated infection requiring surgery or abscess drainage, or requirement of intensive care unit admission. Serogroup D (75.7%) was the predominant isolates. Malignancy (44.7%) was the most prevalent comorbidity. Patients with rapid TTP (<10 h) were more likely to have thrombocytopenia, septic shock, persistent bacteremia, complicated infection, and a higher intensive care unit admission rate. In multivariate logistic regression model, a TTP <10 h was an independent predictor for complicated NTS bacteremia (adjusted odd ratio, 5.683, 95% confidence interval, 2.396–13.482). Our study showed that blood culture TTP provides important diagnostic and prognostic information in the treatment of NTS bacteremia patients. ? 2018 |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/560608 | ISSN: | 0732-8893 | DOI: | 10.1016/j.diagmicrobio.2018.02.005 | SDG/Keyword: | abscess drainage; adult; Article; bacteremia; blood culture; blood group typing; clinical outcome; cohort analysis; comorbidity; controlled study; disease association; female; hospital admission; human; independent variable; infection complication; intensive care unit; major clinical study; male; middle aged; mortality; nonhuman; predictor variable; priority journal; retrospective study; Salmonella; septic shock; thrombocytopenia; aged; bacteremia; blood culture; evaluation study; isolation and purification; procedures; prognosis; Salmonella; salmonellosis; time factor; very elderly; young adult; Adult; Aged; Aged, 80 and over; Bacteremia; Blood Culture; Female; Humans; Male; Middle Aged; Prognosis; Retrospective Studies; Salmonella; Salmonella Infections; Time Factors; Young Adult |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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