Effects of dexmedetomidine on renal microcirculation in ischemia/reperfusion-induced acute kidney injury in rats
Journal
Scientific Reports
Journal Volume
11
Journal Issue
1
Date Issued
2021
Author(s)
Yang, Szu-Jen
Chan, Wing-Sum
NTUH Center of Microcirculation Medical Research (NCMMR)
Abstract
did not differ significantly among the Sham, Dex‒IR, and IR‒Dex groups. Our results showed that pretreatment with dexmedetomidine improved renal microcirculation in rats with IR-induced acute kidney injury. However, the adverse effects of low mean arterial pressure and heart rate might offset the protective effect of dexmedetomidine on organ injury.
SDGs
Publisher
Nature Research
Type
journal article