https://scholars.lib.ntu.edu.tw/handle/123456789/579745
標題: | Rationale and design of the ADAPT-TAVR trial: a randomised comparison of edoxaban and dual antiplatelet therapy for prevention of leaflet thrombosis and cerebral embolisation after transcatheter aortic valve replacement | 作者: | Park, Hanbit Kang, Do-Yoon Ahn, Jung-Min Kim, Kyung Won Wong, Anthony Y T Lam, Simon C C Yin, Wei-Hsian Wei Jeng Lee, Yung-Tsai HSIEN-LI KAO MAO-SHIN LIN Tsung-Yu Ko Kim, Won-Jang Kang, Se Hun Ko, Euihong Kim, Dae-Hee Koo, Hyun Jung Yang, Dong Hyun Kang, Joon-Won Jung, Seung Chai Lee, Jae-Hong Yun, Sung-Cheol Park, Seung-Jung Park, Duk-Woo |
關鍵字: | adult cardiology; thromboembolism; valvular heart disease | 公開日期: | 5-一月-2021 | 卷: | 11 | 期: | 1 | 起(迄)頁: | e042587 | 來源出版物: | BMJ open | 摘要: | Optimal antithrombotic strategy following transcatheter aortic valve replacement (TAVR) is still unknown. We hypothesised that the direct factor Xa inhibitor edoxaban can potentially prevent subclinical leaflet thrombosis and cerebral embolisation compared with conventional dual antiplatelet therapy (DAPT) in patients undergoing TAVR. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/579745 | ISSN: | 2044-6055 | DOI: | 10.1136/bmjopen-2020-042587 | SDG/關鍵字: | acetylsalicylic acid; clopidogrel; edoxaban; antithrombocytic agent; edoxaban; pyridine derivative; thiazole derivative; aortic thrombosis; Article; artificial embolization; cognitive function test; computer assisted tomography; controlled study; diffusion weighted imaging; drug dose reduction; dual antiplatelet therapy; human; incidence; lesion volume; multicenter study; nuclear magnetic resonance imaging; open study; randomized controlled trial; thromboembolism; transcatheter aortic valve implantation; adverse event; aortic valve; aortic valve stenosis; diagnostic imaging; risk factor; South Korea; thrombosis; treatment outcome; Aortic Valve; Aortic Valve Stenosis; Humans; Platelet Aggregation Inhibitors; Pyridines; Republic of Korea; Risk Factors; Thiazoles; Thrombosis; Transcatheter Aortic Valve Replacement; Treatment Outcome |
顯示於: | 醫學系 |
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