https://scholars.lib.ntu.edu.tw/handle/123456789/583340
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Chen, Ying-Ying | en_US |
dc.contributor.author | VIN-CENT WU | en_US |
dc.contributor.author | Huang, Wei-Chieh | en_US |
dc.contributor.author | YU-CHANG YEH | en_US |
dc.contributor.author | Wu, Mai-Szu | en_US |
dc.contributor.author | Huang, Chiu-Ching | en_US |
dc.contributor.author | KWAN-DUN WU | en_US |
dc.contributor.author | Fang, Ji-Tseng | en_US |
dc.contributor.author | Wu, Chih-Jen | en_US |
dc.contributor.author | TAI-SHUAN LAI | en_US |
dc.contributor.author | YU-FENG LIN | en_US |
dc.contributor.author | I-JUNG TSAI | en_US |
dc.contributor.author | CHUN-FU LAI | en_US |
dc.contributor.author | TAO-MIN HUANG | en_US |
dc.contributor.author | TZONG-SHINN CHU | en_US |
dc.contributor.author | YUNG-MING CHEN | en_US |
dc.contributor.author | Chang, Yu-Hsing | en_US |
dc.contributor.author | Lai, Chien-Heng | en_US |
dc.contributor.author | Tseng, Li-Jung | en_US |
dc.contributor.author | Wang, Jian-Jhong | en_US |
dc.contributor.author | Chen, Cheng-Yi | en_US |
dc.contributor.author | Shiao, Chih-Chung | en_US |
dc.contributor.author | Wang, Wei-Jie | en_US |
dc.contributor.author | Lin, Jui-Hsiang | en_US |
dc.contributor.author | Wu, Che-Hsiung | en_US |
dc.contributor.author | Wu, Chih-Jen | en_US |
dc.contributor.author | Lu, Kuo-Cheng | en_US |
dc.contributor.author | Kan, Wei-Chih | en_US |
dc.contributor.author | Huang, Chiu-Ching | en_US |
dc.contributor.author | Chou, Che-Yi | en_US |
dc.contributor.author | Yang, Ya-Fei | en_US |
dc.contributor.author | Tsai, Jen-Pi | en_US |
dc.contributor.author | Hu, Fu-Chang | en_US |
dc.contributor.author | Lee, Chien-Te | en_US |
dc.contributor.author | Chen, Jin-Bor | en_US |
dc.contributor.author | Lee, Chih-Hsiung | en_US |
dc.contributor.author | Lee, Wen-Chin | en_US |
dc.contributor.author | Li, Lung-Chih | en_US |
dc.contributor.author | Chen, Te-Chuan | en_US |
dc.contributor.author | Lin, Hugo You-Hsien | en_US |
dc.contributor.author | Chen, Yung-Chang | en_US |
dc.contributor.author | Lee, Chin-Chan | en_US |
dc.contributor.author | Sun, Chiao-Yin | en_US |
dc.contributor.author | Pan, Heng-Chih | en_US |
dc.contributor.author | Chang, Ming-Yang | en_US |
dc.contributor.author | Jenq, Chang-Chyi | en_US |
dc.contributor.author | Lin, Chan-Yu | en_US |
dc.contributor.author | Chang, Chih-Hsiang | en_US |
dc.contributor.author | Tsai, Tsung-Yu | en_US |
dc.contributor.author | Chen, Cheng-Min | en_US |
dc.contributor.author | Lin, En-Tzu | en_US |
dc.contributor.author | Lin, Cheng-Jua | en_US |
dc.contributor.author | Wu, Pei-Chen | en_US |
dc.contributor.author | Kuo, Feng-Chi | en_US |
dc.contributor.author | Weng, Chih-Jen | en_US |
dc.contributor.author | Chen, Li-Kwang | en_US |
dc.contributor.author | SHUEI-LIONG LIN | en_US |
dc.contributor.author | WEI-SHUN YANG | en_US |
dc.contributor.author | Hsu, Wen-Ding | en_US |
dc.contributor.author | Leu, Jyh-Gang | en_US |
dc.contributor.author | Chang, Jui-Ting | en_US |
dc.contributor.author | Liou, Hung-Hsiang | en_US |
dc.contributor.author | Hsu, Kuo-Hsiung | en_US |
dc.contributor.author | Wu, Ming-Ju | en_US |
dc.contributor.author | Huang, Chun-Te | en_US |
dc.contributor.author | You, Zi-Hong | en_US |
dc.contributor.author | Chang, Chao-Fu | en_US |
dc.contributor.author | Chen, Tzen-Wen | en_US |
dc.contributor.author | Chen, Hsi-Hsien | en_US |
dc.contributor.author | FAN-CHI CHANG | en_US |
dc.contributor.author | Lin, Yen-Chung | en_US |
dc.contributor.author | Wu, Mai-Szu | en_US |
dc.contributor.author | Kao, Chih-Chin | en_US |
dc.contributor.author | Hung, Szu-Chun | en_US |
dc.contributor.author | Kuo, Ko-Lin | en_US |
dc.contributor.author | Wu, Che-Hsiung | en_US |
dc.contributor.author | Tarng, Der-Cherng | en_US |
dc.contributor.author | Chen, Jinn-Yang | en_US |
dc.contributor.author | Yang, Chih-Yu | en_US |
dc.contributor.author | Lee, Kuo-Hua | en_US |
dc.contributor.author | Ko, Sheng-Wen | en_US |
dc.contributor.author | The NSARF, CAKS Group | en_US |
dc.date.accessioned | 2021-09-17T06:12:27Z | - |
dc.date.available | 2021-09-17T06:12:27Z | - |
dc.date.issued | 2018-09-12 | - |
dc.identifier.issn | 2077-0383 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/583340 | - |
dc.description.abstract | (1) Background: Norepinephrine (NE) is the first-line vasoactive agent used in septic shock patients; however, the effect of norepinephrine on dialysis-required septic acute kidney injury (AKI-D) patients is uncertain. (2) Methods: To evaluate the impact of NE on 90-day mortality and renal recovery in septic AKI-D patients, we enrolled patients in intensive care units from 30 hospitals in Taiwan. (3) Results: 372 patients were enrolled and were divided into norepinephrine users and non-users. After adjustment by Inverse probability of treatment weighted (IPTW), there was no significant difference of baseline comorbidities between the two groups. NE users had significantly higher 90-day mortality rate and using NE is a strong predictor of 90-day mortality in the multivariate Cox regression (HR = 1.497, p = 0.027) after adjustment. The generalized additive model disclosed norepinephrine alone exerted a dose⁻dependent effect on 90-day mortality, while other vasoactive agents were not. (4) Conclusion: Using norepinephrine in septic AKI-D patients is associated with higher 90-day mortality and the effect is dose-dependent. Further study to explore the potential mechanism is needed. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Journal of clinical medicine | en_US |
dc.subject | acute kidney injury; critical care; dialysis; norepinephrine; sepsis; vasoactive agents | en_US |
dc.subject | Acute kidney injury; Critical care; Dialysis; Norepinephrine; Sepsis; Vasoactive agents | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | noradrenalin; acute kidney failure; adult; aged; APACHE; Article; cohort analysis; comorbidity assessment; continuous renal replacement therapy; creatinine blood level; disease severity; female; fluid resuscitation; geographic distribution; Glasgow coma scale; heart failure; heart output; hemodialysis; hepatorenal syndrome; hospital discharge; human; intensive care unit; international normalized ratio; major clinical study; male; mean arterial pressure; middle aged; mortality rate; observational study; prospective study; renal replacement therapy; respiratory failure; septic shock; Sequential Organ Failure Assessment Score; urea nitrogen blood level | - |
dc.title | Norepinephrine Administration Is Associated with Higher Mortality in Dialysis Requiring Acute Kidney Injury Patients with Septic Shock | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.3390/jcm7090274 | - |
dc.identifier.pmid | 30213107 | - |
dc.identifier.scopus | 2-s2.0-85085772111 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85085772111 | - |
dc.relation.journalvolume | 7 | en_US |
dc.relation.journalissue | 9 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Anesthesiology-NTUH | - |
crisitem.author.dept | Anesthesiology | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Pediatrics | - |
crisitem.author.dept | Pediatrics-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Medical Education and Bioethics | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Geriatrics and Gerontology-NTUH | - |
crisitem.author.dept | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.dept | Physiology | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Integrated Diagnostics and Therapeutics-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHHC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-7935-0991 | - |
crisitem.author.orcid | 0000-0001-5143-5520 | - |
crisitem.author.orcid | 0000-0002-3339-1509 | - |
crisitem.author.orcid | 0000-0002-0552-372X | - |
crisitem.author.orcid | 0000-0002-4350-7755 | - |
crisitem.author.orcid | 0000-0003-3967-9412 | - |
crisitem.author.orcid | 0000-0003-2109-1522 | - |
crisitem.author.orcid | 0000-0002-9387-0798 | - |
crisitem.author.orcid | 0000-0002-5291-2509 | - |
crisitem.author.orcid | 0000-0002-9241-1258 | - |
crisitem.author.orcid | 0000-0002-1041-5571 | - |
crisitem.author.orcid | 0000-0002-3249-280X | - |
crisitem.author.orcid | 0000-0002-1821-1952 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | NTU Hsin-Chu Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。