https://scholars.lib.ntu.edu.tw/handle/123456789/586905
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | TE-I WENG | en_US |
dc.contributor.author | LIAN-YU CHEN | en_US |
dc.contributor.author | Chen, Ju-Yu | en_US |
dc.contributor.author | GUAN-YUAN CHEN | en_US |
dc.contributor.author | Mou, Chai-Wei | en_US |
dc.contributor.author | Chao, Yu-Liang | en_US |
dc.contributor.author | CHENG-CHUNG FANG | en_US |
dc.date.accessioned | 2021-11-17T02:46:34Z | - |
dc.date.available | 2021-11-17T02:46:34Z | - |
dc.date.issued | 2021-10 | - |
dc.identifier.issn | 0929-6646 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/586905 | - |
dc.description.abstract | The recreational drug γ-hydroxybutyric acid (GHB) is a central nervous system depressant, and can produce euphoria at low doses. GHB is a controlled substance in Taiwan. However, the organic solvents γ-butyrolactone (GBL) and 1,4-butanediol (BD), which are unregulated, may be used as an alternative source of GHB. There is no clinical report of analytically confirmed GHB use in Taiwan. We retrospective reviewed the clinical characteristics from the medical charts between May 2017 and April 2020. The urine samples of patients presented to the emergency departments with drug-related complaints were sent for toxicological analysis. Patients with urine samples detected GHB >10 μg/mL by liquid chromatography/tandem mass spectrometry were included. Overall, 11 men and one woman with an average age of 35.3 ± 8.7 years were included. Most patients co-ingested amphetamine (n = 6) and initially presented with depressed consciousness levels (n = 7). One patient presented with out-of-hospital cardiac arrest and one with respiratory depression. All patients regained consciousness within 6 h of admission. All patients used GBL to evade conviction. Although patients recovered with supportive care, respiratory failure and cardiac arrest occurred after GHB/GBL use. It is important to legislate GBL and BD as controlled chemical substances in Taiwan. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Journal of the Formosan Medical Association = Taiwan yi zhi | en_US |
dc.subject | 1,4-Butanediol; Emergency department; Illicit abused substance; γ-butyrolactone; γ-hydroxybutyric acid | en_US |
dc.title | Characteristics of patients with analytically confirmed γ-hydroxybutyric acid/γ-butyrolactone (GHB/GBL)-related emergency department visits in Taiwan | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.jfma.2021.03.030 | - |
dc.identifier.pmid | 33893011 | - |
dc.identifier.scopus | 2-s2.0-85105057345 | - |
dc.identifier.url | https://scholars.lib.ntu.edu.tw/handle/123456789/561648 | - |
dc.relation.journalvolume | 120 | en_US |
dc.relation.journalissue | 10 | en_US |
dc.relation.pageend | 1920 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Forensic Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.dept | Forensic Medicine | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | Forensic Medicine | - |
crisitem.author.dept | Emergency Medicine | - |
crisitem.author.dept | Emergency Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-8797-1672 | - |
crisitem.author.orcid | 0000-0001-9241-1613 | - |
crisitem.author.orcid | 0000-0002-0505-4089 | - |
crisitem.author.orcid | 0000-0001-5386-6674 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 法醫學科所 |
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