Irreversible Electroporation Treatment With Intraoperative Biliary Stenting for Unresectable Perihilar Cholangiocarcinoma: A Pilot Study
Journal
Frontiers in oncology
Journal Volume
11
Date Issued
2021
Author(s)
Yang, Po-Chih
Chen, Yan-Jun
Li, Xiao-Yong
Cheng, Bing-Bing
Gao, Yu
Zhou, Bai-Zhong
Chen, Sheng-Yang
Hu, Shui-Quan
Zeng, Quan
Abstract
Treating perihilar cholangiocarcinoma (PHCC) is particularly difficult due to the fact that it is usually in an advanced stage at the time of diagnosis. Irreversible electroporation treatment (IRE) involves the local administration of a high-voltage electric current to target lesions without causing damage to surrounding structures. This study investigated the safety and efficacy of using IRE in conjunction with intraoperative biliary stent placement in cases of unresectable PHCC.
Subjects
Jaundice cholangitis; biliary stent; irreversible electroporation; perihilar cholangiocarcinoma (PHCCA); unresectable abdominal neoplasms
SDGs
Other Subjects
alanine aminotransferase; albumin; aspartate aminotransferase; bilirubin; CA 19-9 antigen; cisplatin; gemcitabine; gimeracil plus oteracil potassium plus tegafur; aged; Article; axillary lymph node dissection; bile duct carcinoma; cancer recurrence; cancer staging; cancer survival; cholecystectomy; clinical article; computer assisted tomography; controlled study; drug safety; echography; electroporation; endoscopic retrograde cholangiopancreatography; female; hospitalization; human; laparotomy; lymph node metastasis; male; nuclear magnetic resonance imaging; obstructive jaundice; operation duration; overall survival; progression free survival; prospective study; tumor growth; tumor invasion; tumor volume
Type
journal article