https://scholars.lib.ntu.edu.tw/handle/123456789/588273
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wu, Chia-Hao | en_US |
dc.contributor.author | TING-YU LIAO | en_US |
dc.contributor.author | YUNG-HSUAN CHEN | en_US |
dc.contributor.author | PING-HUNG KUO | en_US |
dc.date.accessioned | 2021-11-30T01:28:16Z | - |
dc.date.available | 2021-11-30T01:28:16Z | - |
dc.date.issued | 2021-10 | - |
dc.identifier.issn | 2051-3380 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/588273 | - |
dc.description.abstract | Electronic (e)-cigarette or vaping product use-associated lung injury (EVALI) is a novel and potentially lethal disease first reported in the United States. We report the case of a 56-year-old man who presented to our hospital with dyspnoea and cough lasting for 2 months after using an e-cigarette for approximately 50 puffs over 2 weeks. Physical examination revealed crackles in the left lower lung. High-resolution computed tomography (HRCT) showed consolidation and ground-glass opacities in both lungs. The baseline forced vital capacity (FVC) and diffusion capacity for carbon monoxide (DLCO) were 65.7% and 63.9% of the predicted, respectively. Lung biopsy revealed organizing pneumonia with focal fibrosis. In addition to prednisolone, he was treated with a low-dose pirfenidone (200 mg three times per day) due to the persistence of a mild cough, exertional dyspnoea and basal crackles after discharge. His symptoms and FVC significantly improved, but the recovery of the DLCO was slow. The follow-up HRCT demonstrated only minimal fibrotic changes. To our knowledge, this was the first reported case of EVALI successfully treated with a combination of corticosteroid and antifibrotic agents. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Respirology case reports | en_US |
dc.subject | corticosteroid; e‐cigarette or vaping product use associated lung injury (EVALI); organizing pneumonia; pirfenidone | en_US |
dc.subject | corticosteroid; e-cigarette or vaping product use associated lung injury (EVALI); organizing pneumonia; pirfenidone | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | antifibrotic agent; azathioprine; corticosteroid; cyclophosphamide; methylprednisolone; mycophenolic acid; pirfenidone; prednisolone; adult; Article; blood pressure; breathing rate; case report; clinical article; computer assisted tomography; corticosteroid therapy; coughing; crackle; diffusing capacity for carbon monoxide; dyspnea; exertional dyspnea; forced expiratory volume; forced vital capacity; high resolution computer tomography; human; leukocyte count; low drug dose; lung biopsy; lung function test; male; middle aged; oxygen saturation; physical examination; vaping associated lung injury | - |
dc.title | Treatment of electronic cigarette or vaping product use-associated lung injury (EVALI) by corticosteroid and low-dose pirfenidone: Report of a case | en_US |
dc.identifier.doi | 10.1002/rcr2.845 | - |
dc.identifier.pmid | 34584727 | - |
dc.identifier.scopus | 2-s2.0-85115716640 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85115716640 | - |
dc.relation.journalvolume | 9 | en_US |
dc.relation.journalissue | 10 | en_US |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Integrated Diagnostics and Therapeutics-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Center of Sleep Disorder | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-8220-9892 | - |
crisitem.author.orcid | 0000-0003-3756-3395 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。