Assessing tumor angiogenesis using dynamic contrast-enhanced integrated magnetic resonance-positron emission tomography in patients with non-small-cell lung cancer
Journal
BMC cancer
Journal Volume
21
Journal Issue
1
Date Issued
2021-04-01
Author(s)
Abstract
Angiogenesis assessment is important for personalized therapeutic intervention in patients with non-small-cell lung cancer (NSCLC). This study investigated whether radiologic parameters obtained by dynamic contrast-enhanced (DCE)-integrated magnetic resonance-positron emission tomography (MR-PET) could be used to quantitatively assess tumor angiogenesis in NSCLC.
Subjects
Angiogenesis inhibitors; Personalized medicine; Radiologic biomarkers; Survival
SDGs
Other Subjects
angiogenesis inhibitor; angiogenin; angiopoietin 1; bevacizumab; biological marker; fluorodeoxyglucose; gadobutrol; ramucirumab; vasculotropin A; adult; advanced cancer; aged; angiogenesis; apparent diffusion coefficient; Article; cancer patient; cancer staging; cohort analysis; controlled study; dynamic contrast enhanced integrated magnetic resonance positron emission tomography; dynamic contrast-enhanced magnetic resonance imaging; enzyme linked immunosorbent assay; extracellular extravascular volume fraction; female; human; major clinical study; male; maximum standardized uptake value; metabolic tumor volume; non small cell lung cancer; overall survival; plasma volume; prospective study; protein blood level; radiological parameters; reverse reflux rate constant; very elderly; volume transfer constant; diagnostic imaging; lung tumor; middle aged; mortality; non small cell lung cancer; nuclear magnetic resonance imaging; personalized medicine; positron emission tomography; procedures; survival analysis; x-ray computed tomography; Adult; Aged; Aged, 80 and over; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Female; Humans; Lung Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Precision Medicine; Prospective Studies; Survival Analysis; Tomography, X-Ray Computed
Type
journal article