https://scholars.lib.ntu.edu.tw/handle/123456789/592050
標題: | Associations of chronic urticaria with atopic and autoimmune comorbidities: a nationwide population-based study | 作者: | HSIEN-YI CHIU Muo C.-H. Sung F.-C. |
公開日期: | 2018 | 出版社: | Blackwell Publishing Ltd | 卷: | 57 | 期: | 7 | 起(迄)頁: | 822-829 | 來源出版物: | International Journal of Dermatology | 摘要: | Background: Most cases of chronic urticaria (CU) are idiopathic. Circumstantial evidence suggests that some CU cases have an autoimmune pathogenesis. Previous research indicates that a substantial percentage of patients with CU have an atopic background. Objectives: This study aims to examine the association between CU, and atopic and autoimmune diseases. Methods: This population-based retrospective cohort study identified 9,332 patients with CU and 37,328 controls matched for age, sex, and number of dermatological clinic visits from the Taiwan National Health Insurance Research Database for 2004–2009. Using multiple logistic regression, we estimated odds ratios (OR) and 95% confidence intervals (CI) for associations of CU with atopic and autoimmune diseases. Results: CU was most strongly associated with Kawasaki disease (modified OR, 2.76; 95% CI 1.15–6.63), followed by Henoch–Sch?nlein purpura (HSP), atopic dermatitis (AD), systemic lupus erythematosus (SLE), allergic rhinitis (AR), autoimmune thyroid diseases, Sj?gren syndrome, inflammatory bowel disease (IBD), and asthma, which had the lowest adjusted OR (1.11; 95% CI 1.01–1.22) among comorbidities significantly associated with CU. The associations varied in relation to age, group, and sex. Among women, CU was significantly associated with AD, AR, autoimmune thyroid diseases, SLE, vitiligo, and HSP. Among men, CU was significantly associated with AD, AR, autoimmune thyroid diseases, Kawasaki disease, and IBD. Conclusion: CU is associated with atopic/autoimmune diseases. Increased awareness of atopic and autoimmune comorbidities may be warranted for patients with CU. ? 2018 The International Society of Dermatology |
URI: | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85048211103&doi=10.1111%2fijd.14000&partnerID=40&md5=5c32e120f2e2103b3d70aa4e872b87b6 https://scholars.lib.ntu.edu.tw/handle/123456789/592050 |
ISSN: | 0011-9059 | DOI: | 10.1111/ijd.14000 | SDG/關鍵字: | adult; age; allergic rhinitis; anaphylactoid purpura; Article; asthma; atopic dermatitis; atopy; autoimmune disease; autoimmune thyroiditis; chronic urticaria; cohort analysis; comorbidity; controlled study; disease association; female; human; inflammatory bowel disease; major clinical study; male; mucocutaneous lymph node syndrome; onset age; psoriasis; retrospective study; sex difference; Sjoegren syndrome; systemic lupus erythematosus; Taiwan; vitiligo; allergic rhinitis; anaphylactoid purpura; asthma; atopic dermatitis; autoimmune thyroiditis; case control study; chronic disease; comorbidity; inflammatory bowel disease; middle aged; mucocutaneous lymph node syndrome; odds ratio; sex factor; Sjoegren syndrome; systemic lupus erythematosus; urticaria; vitiligo; young adult; Adult; Asthma; Case-Control Studies; Chronic Disease; Comorbidity; Dermatitis, Atopic; Female; Humans; Inflammatory Bowel Diseases; Lupus Erythematosus, Systemic; Male; Middle Aged; Mucocutaneous Lymph Node Syndrome; Odds Ratio; Purpura, Schoenlein-Henoch; Retrospective Studies; Rhinitis, Allergic; Sex Factors; Sjogren's Syndrome; Taiwan; Thyroiditis, Autoimmune; Urticaria; Vitiligo; Young Adult |
顯示於: | 醫學系 |
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