https://scholars.lib.ntu.edu.tw/handle/123456789/592397
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | LI-CHUN CHANG | en_US |
dc.contributor.author | HAN-MO CHIU | en_US |
dc.contributor.author | CHIA-TUNG SHUN | en_US |
dc.contributor.author | JIN-TUNG LIANG | en_US |
dc.contributor.author | Lin, Jaw-Town | en_US |
dc.contributor.author | CHIEN-CHUAN CHEN | en_US |
dc.contributor.author | YI-CHIA LEE | en_US |
dc.contributor.author | MING-SHIANG WU | en_US |
dc.date.accessioned | 2022-01-14T08:59:50Z | - |
dc.date.available | 2022-01-14T08:59:50Z | - |
dc.date.issued | 2014-12-31 | - |
dc.identifier.issn | 1471-230X | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/592397 | - |
dc.description.abstract | Investigations of genetic alterations and correlations with histology or morphology could provide further insights into colorectal carcinogenesis. Nevertheless, such genetic changes were less investigated in adenoma stage and a comprehensive survey of oncogenic mutations in EGFR signaling pathway according to different morphologic subtypes has not been performed. | en_US |
dc.language.iso | en | en_US |
dc.publisher | BIOMED CENTRAL LTD | en_US |
dc.relation.ispartof | BMC gastroenterology | en_US |
dc.subject | Gene mutation; Non-polypoid colorectal neoplasm; EGFR; LATERALLY-SPREADING TUMORS; K-RAS MUTATIONS; CHINESE POPULATION; SERRATED PATHWAY; COLON CANCERS; POOR SURVIVAL; STOOL DNA; FLAT; CARCINOMA; PREVALENCE | en_US |
dc.subject.classification | [SDGs]SDG3 | - |
dc.subject.other | B Raf kinase; epidermal growth factor receptor; epidermal growth factor receptor 2; protein kinase B; B Raf kinase; KRAS protein, human; oncoprotein; phosphatidylinositol 3 kinase; PIK3CA protein, human; Ras protein; adult; aged; AKT gene; Article; BRAF gene; cancer classification; cancer staging; carcinogenesis; colorectal adenoma; controlled study; disease severity; EGFR gene; epigenetics; exon; female; gene; genetic association; HER2 gene; histopathology; human; human tissue; immunohistochemistry; major clinical study; male; middle aged; morphology; mutational analysis; oncogene K ras; PIK3CA gene; tumor volume; adenoma; colorectal tumor; genetics; mutation; nucleotide sequence; pathology; Adenoma; Aged; Colorectal Neoplasms; DNA Mutational Analysis; Female; Humans; Male; Middle Aged; Mutation; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; ras Proteins | - |
dc.title | Mutational profiles of different macroscopic subtypes of colorectal adenoma reveal distinct pathogenetic roles for KRAS, BRAF and PIK3CA | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1186/s12876-014-0221-y | - |
dc.identifier.pmid | 25551625 | - |
dc.identifier.scopus | 2-s2.0-84965084561 | - |
dc.identifier.isi | WOS:000347984300001 | - |
dc.identifier.url | https://scholars.lib.ntu.edu.tw/handle/123456789/544688 | - |
dc.relation.pages | 221 | en_US |
dc.relation.journalvolume | 14 | en_US |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.openairetype | journal article | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
item.cerifentitytype | Publications | - |
item.fulltext | no fulltext | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Integrated Diagnostics and Therapeutics-NTUH | - |
crisitem.author.dept | Forensic Medicine | - |
crisitem.author.dept | Surgery | - |
crisitem.author.dept | Surgery-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0001-5325-3974 | - |
crisitem.author.orcid | 0000-0003-2786-8056 | - |
crisitem.author.orcid | 0000-0002-0468-4468 | - |
crisitem.author.orcid | 0000-0002-0264-7735 | - |
crisitem.author.orcid | 0000-0002-8160-1216 | - |
crisitem.author.orcid | 0000-0002-1940-6428 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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