|Title:||Surface PEGylation via Ultrasonic Spray Deposition for the Biofouling Mitigation of Biomedical Interfaces||Authors:||Tang, Shuo Hsi
Chou, Li Hui
Lan, Ding Hung
Dizon, Gian Vincent
Yeh, Chih Chen
|Keywords:||antifouling | biomedical interfaces | blood typing | PEGylated copolymer | spray-coating||Issue Date:||1-Jan-2021||Source:||ACS Applied Bio Materials||Abstract:||
Air plasma and spray technology are common methods for surface modification. In this study, air plasma is used to generate hydroxyl groups on various material surfaces. Then random copolymers of styrene and ethylene glycol methacrylate (PS-r-PEGMA) are spray-coated to achieve coating densities ranging between 0.1 and 0.6 mg/cm2. PS50-r-PEGMA50 led to the best overall antifouling properties, while a coating density of 0.3 mg/cm2 was enough to significantly reduce biofouling. This surface modification technique enabled efficient modification of a wide range of materials and biofouling reduction by at least 75% on polymeric surfaces (polystyrene, polyvinylidene fluoride, poly(tetrafluoroethylene), polydimethylsiloxane), metallic surfaces (steel, titanium alloy), or ceramic surface (glass). Applied to the modification of well plate used for blood-typing, this antifouling modification permitted to greatly increase the signal sensitivity (×4).
|Appears in Collections:||材料科學與工程學系|
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