Circulatory Inflammatory Mediators in the Prediction of Anti-Tuberculous Drug-Induced Liver Injury Using RUCAM for Causality Assessment
Journal
Biomedicines
Journal Volume
9
Journal Issue
8
Start Page
891
Date Issued
2021-07-25
Abstract
Anti-tuberculous (TB) medications are common causes of drug-induced liver injury (DILI). Limited data are available on systemic inflammatory mediators as biomarkers for predicting DILI before treatment. We aimed to select predictive markers among potential candidates and to formulate a predictive model of DILI for TB patients.
Subjects
RUCAM (Roussel Uclaf Causality Assessment Method); drug-induced liver injury; hepatotoxicity; inflammatory mediators; prediction model; tuberculosis
SDGs
Publisher
MDPI
Type
journal article