https://scholars.lib.ntu.edu.tw/handle/123456789/608806
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | Wei-Sin Yang | en_US |
dc.contributor.author | Pei-Chun Chen | en_US |
dc.contributor.author | Hsiu-Ching Hsu | en_US |
dc.contributor.author | TA-CHEN SU | en_US |
dc.contributor.author | HUNG-JU LIN | en_US |
dc.contributor.author | MING-FONG CHEN | en_US |
dc.contributor.author | Yuan-Teh Lee | en_US |
dc.contributor.author | KUO-LIONG CHIEN | en_US |
dc.date.accessioned | 2022-04-28T12:31:32Z | - |
dc.date.available | 2022-04-28T12:31:32Z | - |
dc.date.issued | 2018-01 | - |
dc.identifier.issn | 0026-0495 | - |
dc.identifier.uri | https://www.scopus.com/inward/record.uri?eid=2-s2.0-85042457190&doi=10.1016%2fj.metabol.2018.01.006&partnerID=40&md5=1b6dc646f5fdae0fe2dd6259b024c261 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/608806 | - |
dc.identifier.uri | https://pubmed.ncbi.nlm.nih.gov/29410352/ | - |
dc.description.abstract | Background: We investigated the association between plasma saturated fatty acids (SFAs) and the risk of metabolic syndrome among ethnic Chinese adults in Taiwan who attended a health check-up center. Methods: A case-control study based on 1000 cases of metabolic syndrome and 1:1 matched control participants (mean age, 54.9 ± 10.7 y; 36% females) were recruited. Metabolic syndrome was defined according to the criteria of the International Diabetes Federation. Gas chromatography was used to measure the distribution of fatty acids in plasma (% of total fatty acids). Results: Even-chain SFAs, including 14:0, 16:0, and 18:0, were associated with metabolic syndrome; the adjusted odds ratio [OR] and 95% confidence interval [CI] per standard deviation [SD] difference was 3.32, [1.98-5.59]; however, very-long-chain SFAs, including 20:0, 21:0, 22:0, 23:0, and 24:0, were inversely associated with metabolic syndrome. The adjusted OR [95% CI] per SD difference was 0.67 [0.58-0.78]. The area under the receiver operative characteristic curve increased from 0.814 in the basic model to 0.815 (p = 0.54, compared with the basic model), 0.818 (p < 0.0001), and 0.820 (p < 0.0001) after adding odd-chain, even-chain, and very-long chain SFAs. A meta-analysis based on 12 studies showed that the summarized OR for type 2 diabetes mellitus was 1.16 [0.96-1.41] for the top versus bottom SFAs. Conclusions: Different carbon numbers of SFAs have been shown to have differential effects on the status of metabolic syndrome, implying that SFAs are not homogenous for the effects. | en_US |
dc.language.iso | en | en_US |
dc.publisher | W.B. Saunders | en_US |
dc.relation.ispartof | Metabolism: Clinical and Experimental | en_US |
dc.subject | Meta-analysis; Metabolic syndrome; Saturated fatty acids | en_US |
dc.title | Differential effects of saturated fatty acids on the risk of metabolic syndrome: a matched case-control and meta-analysis study | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1016/j.metabol.2018.01.006 | - |
dc.identifier.pmid | 29410352 | - |
dc.identifier.scopus | 2-s2.0-85042457190 | - |
dc.relation.pages | 42-49 | en_US |
dc.relation.journalvolume | 83 | en_US |
item.languageiso639-1 | en | - |
item.fulltext | no fulltext | - |
item.grantfulltext | none | - |
item.openairetype | journal article | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.cerifentitytype | Publications | - |
crisitem.author.dept | Environmental and Occupational Medicine | - |
crisitem.author.dept | Environmental and Occupational Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUHBH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Epidemiology and Preventive Medicine | - |
crisitem.author.dept | Public Health | - |
crisitem.author.orcid | 0000-0001-7523-7166 | - |
crisitem.author.orcid | 0000-0003-1046-2308 | - |
crisitem.author.orcid | 0000-0001-6633-7632 | - |
crisitem.author.orcid | 0000-0003-4979-8351 | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Public Health | - |
crisitem.author.parentorg | College of Public Health | - |
顯示於: | 流行病學與預防醫學研究所 |
在 IR 系統中的文件,除了特別指名其著作權條款之外,均受到著作權保護,並且保留所有的權利。