https://scholars.lib.ntu.edu.tw/handle/123456789/626829
Title: | Use of nicorandil is associated with increased risk of incident atrial fibrillation | Authors: | CHIEN-CHANG LEE SHENG-NAN CHANG Tehrani, Babak Liu, Sot Shih-Hung Chan, Chia-Ying Hsu, Wan-Ting Huang, Tzu-Yun PANG-SHUO HUANG HWANG, JUEY-JEN JIEN-JIUN CHEN CHIA-TI TSAI |
Keywords: | atrial fibrillation; nicorandil; translational study | Issue Date: | 9-Sep-2022 | Publisher: | IMPACT JOURNALS LLC | Journal Volume: | 14 | Journal Issue: | 17 | Start page/Pages: | 6975 | Source: | Aging | Abstract: | Nicorandil will activate ATP-sensitive potassium channel (KATP). However, activation of potassium channels plays an important role in the mechanism of atrial fibrillation (AF) or atrial flutter (AFL). Whether use of nicorandil might contribute to initiation and/or perpetuation of AF/AFL remained unknown. We determined the relationship between use of nicorandil and risk of atrial fibrillation and determined its molecular mechanism. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/626829 | ISSN: | 1945-4589 | DOI: | 10.18632/aging.204259 |
Appears in Collections: | 醫學院附設醫院 (臺大醫院) |
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