https://scholars.lib.ntu.edu.tw/handle/123456789/627499
標題: | Translation suppression underlies the restrained COVID-19 mRNA vaccine response in the high-risk immunocompromised group | 作者: | Kim, Kangsan Narasimhan, Madhusudhanan Mahimainathan, Lenin Zhang, Ray Araj, Ellen Kim, Elizabeth Tharpe, William Greenberg, Benjamin M Greenberg, David E Li, Quan-Zhen CHI-AN CHENG Sarode, Ravi Malladi, Srinivas Muthukumar, Alagarraju |
關鍵字: | covid-19 mRNA vaccines; immunocompromised patients; mycophenolate; sirolimus; tacrolimus; translation suppression | 公開日期: | 十月-2022 | 出版社: | FRONTIERS MEDIA SA | 卷: | 13 | 來源出版物: | Frontiers in immunology | 摘要: | Immunocompromised (IC) patients show diminished immune response to COVID-19 mRNA vaccines (Co-mV). To date, there is no 'empirical' evidence to link the perturbation of translation, a rate-limiting step for mRNA vaccine efficiency (VE), to the dampened response of Co-mV. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/627499 | ISSN: | 1664-3224 | DOI: | 10.3389/fimmu.2022.1020165 |
顯示於: | 藥學系 |
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