https://scholars.lib.ntu.edu.tw/handle/123456789/629214
DC 欄位 | 值 | 語言 |
---|---|---|
dc.contributor.author | JIN-YING LU | en_US |
dc.contributor.author | Ou, Horng-Yih | en_US |
dc.contributor.author | Wu, Chung-Ze | en_US |
dc.contributor.author | Yang, Chwen-Yi | en_US |
dc.contributor.author | Jiang, Ju-Ying | en_US |
dc.contributor.author | Lu, Chieh-Hsiang | en_US |
dc.contributor.author | YI-DER JIANG | en_US |
dc.contributor.author | TIEN-JYUN CHANG | en_US |
dc.contributor.author | YI-CHENG CHANG | en_US |
dc.contributor.author | Hsieh, Meng-Lun | en_US |
dc.contributor.author | WAN-CHEN WU | en_US |
dc.contributor.author | HUNG-YUAN LI | en_US |
dc.contributor.author | Du, Ye-Fong | en_US |
dc.contributor.author | Lin, Ching-Han | en_US |
dc.contributor.author | Hung, Hao-Chang | en_US |
dc.contributor.author | Tien, Kai-Jen | en_US |
dc.contributor.author | Yeh, Nai-Cheng | en_US |
dc.contributor.author | Lee, Shang-Yu | en_US |
dc.contributor.author | Yu, Hui-I | en_US |
dc.contributor.author | LEE-MING CHUANG | en_US |
dc.date.accessioned | 2023-03-13T02:29:31Z | - |
dc.date.available | 2023-03-13T02:29:31Z | - |
dc.date.issued | 2023-02-15 | - |
dc.identifier.issn | 2045-2322 | - |
dc.identifier.uri | https://scholars.lib.ntu.edu.tw/handle/123456789/629214 | - |
dc.description.abstract | Transcutaneous electrical nerve stimulator (TENS) has been demonstrated to be beneficial in glycemic control in animal models, but its application in humans has not been well studied. We randomly assigned 160 patients with type 2 diabetes on oral antidiabetic drugs 1:1 to the TENS study device (n = 81) and placebo (n = 79). 147 (92%) randomized participants (mean [SD] age 59 [10] years, 92 men [58%], mean [SD] baseline HbA1c level 8.1% [0.6%]) completed the trial. At week 20, HbA1c decreased from 8.1% to 7.9% in the TENS group (- 0.2% [95% CI - 0.4% to - 0.1%]) and from 8.1% to 7.8% in the placebo group (- 0.3% [95% CI - 0.5% to - 0.2%]) (P = 0.821). Glycemic variability, measured as mean amplitude of glycemic excursion (MAGE) at week 20 were significantly different in the TENS group vs. the placebo group (66 mg/dL [95% CI 58, 73] vs. 79 mg/dL [95% CI 72, 87]) (P = 0.009). Our study provides the clinical evidence for the first time in humans that TENS does not demonstrate a statistically significant HbA1c reduction. However, it is a safe complementary therapy to improve MAGE in patients with type 2 diabetes. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Scientific reports | en_US |
dc.title | A randomized trial on the effect of transcutaneous electrical nerve stimulator on glycemic control in patients with type 2 diabetes | en_US |
dc.type | journal article | en |
dc.identifier.doi | 10.1038/s41598-023-29791-7 | - |
dc.identifier.pmid | 36792682 | - |
dc.identifier.scopus | 2-s2.0-85148115090 | - |
dc.identifier.url | https://api.elsevier.com/content/abstract/scopus_id/85148115090 | - |
dc.relation.journalvolume | 13 | en_US |
dc.relation.journalissue | 1 | en_US |
item.openairetype | journal article | - |
item.cerifentitytype | Publications | - |
item.openairecristype | http://purl.org/coar/resource_type/c_6501 | - |
item.fulltext | no fulltext | - |
item.languageiso639-1 | en | - |
item.grantfulltext | none | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHBH | - |
crisitem.author.dept | Medicine-NTUCC | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Laboratory Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Medical Genomics and Proteomics | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine-NTUHBH | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine | - |
crisitem.author.dept | Internal Medicine-NTUH | - |
crisitem.author.orcid | 0000-0002-0263-0669 | - |
crisitem.author.orcid | 0000-0002-4276-5461 | - |
crisitem.author.orcid | 0000-0001-9437-5847 | - |
crisitem.author.orcid | 0000-0002-8077-5011 | - |
crisitem.author.orcid | 0000-0002-2731-5331 | - |
crisitem.author.orcid | 0000-0001-9644-2855 | - |
crisitem.author.orcid | 0000-0003-0978-2662 | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | National Taiwan University Cancer Center (NTUCC) | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | National Taiwan University Hospital Bei-Hu Branch | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | College of Medicine | - |
crisitem.author.parentorg | National Taiwan University Hospital | - |
顯示於: | 醫學系 |
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