Alpha‐fetoprotein (AFP) in Gynecological Tumors

AFP in 262 patients with genital malignancy, 28 with non‐genital malignancy, 58 with benign ovarian tumors, 56 with hydatidiform mole, 12 with choriocarcinoma and 83 healthy females was determined by AFP radioimmunoassay. It was found in 1 patient with corpus cancer, 5 with ovarian malignancy, 4 with testicular malignancy and 2 with partial hydatidiform mole. The importance of immunocytochemical localization of tumor markers is emphasized and the concept of apparent half‐life (AHL) of AFP is introduced. © 1981 Japanese Society of Obstetrics and Gynaecology