https://scholars.lib.ntu.edu.tw/handle/123456789/635920
Title: | S100A8, S100A9 and S100A8/A9 heterodimer as novel cachexigenic factors for pancreatic cancer-induced cachexia | Authors: | WEI-CHIH LIAO Chen, Chih-Ta Tsai, You-Shu Wang, Xin-Ya Chang, Yen-Tzu Wu, Ming-Shiang LU-PING CHOW |
Keywords: | Biomarker; Cachexia; Muscle atrophy; Pancreatic cancer; S100A8; S100A9 | Issue Date: | 6-Jun-2023 | Journal Volume: | 23 | Journal Issue: | 1 | Source: | BMC cancer | Abstract: | Cancer cachexia, occurring in ~ 80% pancreatic cancer (PC) patients overall, is a paraneoplastic syndrome mediated by cancer-induced systemic inflammation and characterized by weight loss and skeletal muscle wasting. Identifying clinically relevant PC-derived pro-inflammatory factors with cachexigenic potential may provide novel insights and therapeutic strategies. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/635920 | ISSN: | 1471-2407 | DOI: | 10.1186/s12885-023-11009-8 |
Appears in Collections: | 生物化學暨分子生物學科研究所 |
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