https://scholars.lib.ntu.edu.tw/handle/123456789/639018
Title: | HSV-1 in a case of intractable glaucoma with rapid progress of cataract after transscleral cyclophotocoagulation | Authors: | Chung, Hui Chuan Tsai, I. Lun Tsai, Ching Yao Liou, Shiow Wen LIN-CHUNG WOUNG |
Keywords: | Herpes simplex virus (HSV) | Intractable glaucoma | Polymerase chain reaction (PCR) | Rapid cataract formation | Transscleral cyclophotocoagulation (TSCPC) | Issue Date: | 1-Jan-2011 | Journal Volume: | 1 | Journal Issue: | 1 | Source: | Taiwan Journal of Ophthalmology | Abstract: | A 22-year-old female patient received penetrating keratoplasty (PK) of her right eye for ocular rosacea complicated with corneal perforation. Intraocular pressure (IOP) fluctuated and could not be well controlled by full antiglaucomatous agents after surgery. Therefore transscleral diode laser cyclophotocoagulation (TSCPC) was performed for the intractable glaucoma one year after PK. Unfortunately, acute cataract formation was noted 50 days after the laser treatment. Pigmented keratic precipitates (KPs) developed and IOP rose subsequently. Cataract extraction with intraocular lens implantation combined with trabeculectomy was performed 3 months later. Polymerase chain reaction (PCR) tests of the aqueous humor to detect cytomegalovirus (CMV) and herpes simplex virus (HSV) were negative. However, HSV type I DNA was detected in the lenticular material and excised trabecular tissue. Trabeculitis caused by herpetic infection could be the reason of fluctuated and intractable IOP elevation. The virus hidden in the intraocular tissue could be reactivated by TSCPC and result in cataract formation. Therefore, performing TSCPC in a phakic eye with atypical IOP presentation should be undertaken with caution. © 2011, The Ophthalmologic Society of Taiwan. Published by Elsevier Taiwan LLC. |
URI: | https://scholars.lib.ntu.edu.tw/handle/123456789/639018 | ISSN: | 22115056 | DOI: | 10.1016/j.tjo.2011.09.002 |
Appears in Collections: | 醫學系 |
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