Lovastatin-Induced Differentiation with Vildagliptin-Inhibited Dipeptidyl Peptidase-IV (DPP-IV) Activity for Tumor Therapy in Anaplastic Thyroidcancer Using Proteomics Andand Nude Mice Model

Project title

Lovastatin 啟動FLOT1合併Vildagliptin 抑制二胜肽基脢-Ⅳ 誘導甲狀腺未分化癌及腺癌細胞分化及之蛋白質體學及裸鼠模型研究

Internal ID

NSC102-2314-B002-028

Principal Investigator

Start Date

August 1, 2013

End Date

July 12, 2014

Partner Organizations

Keywords

Lovastatin(史達汀)

Vildagliptin

閥蛋白(FLOT1)

甲狀腺未分化癌

甲狀
腺濾泡癌

蛋白質學

裸鼠

細胞凋亡

腫瘤分化

氧化硫胺素 (Oxythiamine)

Lovastatin

Vildagliptin

FLOT1

Anaplastic thyroid cancer

Follicular thyroid
cancer

Proteomics

Nude mouse

Apoptosis

Differentiation

Dipeptidyl peptidase-IV
(DPP-IV)