Mechanistic Studies on Inflammatory Microenvironment as a Mediator of Dynamic Genome-Plasticity Leading to Tumorigenesis

Project title

探討發炎微環境如何影響造成之基因體可塑性進而促成癌症發生與進程

Internal ID

MOST103-2320-B002-063-MY3

Principal Investigator

Start Date

August 1, 2014

End Date

July 12, 2015

Partner Organizations

Project Web Site

Keywords

DNA 拓樸異構酶

拓樸酶造成的 DNA 斷裂

微生物易位

發炎微環境

一氧化氮與
氮化壓力

基因突變可塑性

腫瘤發生

DNA Topoisomerase

Topoisomerase-mediated DNA Breakage

Microbiota
Translocation

Inflammatory Microenvironment

Nitric oxide and Nitrosylated stress

Genome Plasticity and Mutagenesis

Tumorigenesis