https://scholars.lib.ntu.edu.tw/handle/123456789/69053
標題: | Biocompatible, Surface Functionalized Mesoporous Titania Nanoparticles for Intracellular Imaging and Anticancer Drug Delivery. | 作者: | Wu, Kevin C.-W. Yamauchi, Yusuke Hong, Chen-Yu Yang, Ya-Huei Liang, Yung-He Funatsu, Takashi KEVIN CHIA-WEN WU |
公開日期: | 2011 | 起(迄)頁: | 5232 | 來源出版物: | Chemical Communications | 摘要: | Mesoporous titania nanoparticles (MTNs) with excellent biocompatibility (LC50 ? 400 μg mL?1) and a large surface area (ca. 237.3 m2 g?1) were synthesized and further functionalized with a phosphate-containing fluorescent molecule (i.e. flavin mononucleotide; FMN) and loaded with an anticancer drug (i.e. Doxorubicin) for successful intracellular bioimaging and drug delivery, respectively, in human breast cancer cells BT-20. ? The Royal Society of Chemistry 2011. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/257212 | DOI: | 10.1039/C1CC10659G 10.1039/c1cc10659g |
SDG/關鍵字: | doxorubicin; flavine mononucleotide; mesoporous titania nanoparticle; nanoparticle; phosphate; pralidoxime mesilate; titanium derivative; titanium dioxide; unclassified drug; article; biocompatibility; breast cancer; cancer cell; cell proliferation; controlled study; cytotoxicity; drug delivery system; female; human; human cell; porosity; surface property; transmission electron microscopy |
顯示於: | 化學工程學系 |
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