The Institute of Immunology was founded in 1992. Currently, the Institute has six full-time faculty and six joint and adjunct members. The facility is well equipped to do basic and clinical immunology research, as it is in proximity to an animal facility, library, and the hospital. Our faculty members are actively engaged in immunology research. Their research areas encompass hematopoiesis, infection, cancer, autoimmunity, T cell regulation, and T cell differentiation. Our faculty members published 5-6 papers in the famous immunology journal each year, including the Journal of Immunology, Blood, Journal of Virology, Infection and Immunity. Dr. Ping-Ning Hsu’s research focused on the regulation of apoptosis signal transuction and the development of autoimmune disease. His research has recently identified TRAIL as a co-stimulatory molecule for T cell activation. Dr. Betty Wu-Hsieh’s research has recently established an mice animal model for Dengue virus infection. Dr. Jean-San Chia’s research is focused on bacterial-host interaction, and he has recently established an infectious endocarditis mice animal model. Dr. Chien-Kuo Lee’s research focused on the regulation of immune response by Stat molecules. He has recently identified Stat3 as a positive regulator of B lymphocyte development. Dr. Shi-Chuen Maiw’s research interest is to study the transcription factors in regulation of Th1/Th2 differentiation, regulation of cytokine gene expression. Dr. Chia-Chi Ku’s research interest is to investigate the CD8 T cell differentiation, viral pathogenesis T cell response to viral infections.