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.National Taiwan University / 國立臺灣大學
Project / 研究計畫
Galnt2 Alters the O-Glycosylation of Plexin-B2 and Affects Malignant Characteristics of Ovarian Cancer Cells
Galnt2 Alters the O-Glycosylation of Plexin-B2 and Affects Malignant Characteristics of Ovarian Cancer Cells
Details
Primary Data
Project title
GALNT2改變Plexin-B2的O型醣基化進而影響卵巢癌細胞惡性特質
Internal ID
NSTC113-2314-B002-253
Principal Investigator
CHI-HAU CHEN
Start Date
August 1, 2024
End Date
July 31, 2025
Investigators
MIN-CHUAN HUANG
Organizations
Obstetrics & Gynecology
Partner Organizations
National Science and Technology Council
Description
Keywords
GALNT2
Plexin-B2
O-glycosylation
Description
卵巢癌是婦科惡性腫瘤中死亡率最高的,雖然婦癌的治療在近幾世紀中有些許的進展,但是後期或復發的卵巢癌存活率仍是相當差,因此有迫切的需要去深入了解卵巢癌的癌化機轉及發展新的治療方法來改善病人的預後。本計劃完成除具有釐清GALNT2影響Plexin-B2之O-醣基化在卵巢癌癌化的角色之學術價值,亦有助於開發具潛力之癌症治療分子標靶。
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