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.National Taiwan University / 國立臺灣大學
Project / 研究計畫
Investigate the Impact and Molecular Mechanisms of Slc35a2 on Clinical Prognosis and Malignant Cellular Behaviors in Neuroblastoma
Investigate the Impact and Molecular Mechanisms of Slc35a2 on Clinical Prognosis and Malignant Cellular Behaviors in Neuroblastoma
Details
Primary Data
Project title
探討SLC35A2在神經母細胞瘤對臨床預後與癌細胞惡性行為的影響及其分子機制
Internal ID
NSTC113-2314-B002-265
Principal Investigator
HSIU-HAO CHANG
Start Date
August 1, 2024
End Date
July 31, 2025
Investigators
MIN-CHUAN HUANG
WEN-MING HSU
NENG-YU LIN
Organizations
Pediatrics
Partner Organizations
National Science and Technology Council
Description
Keywords
Autophagy
neuroblastoma
nucleotide sugar transporter
SLC35A2
Description
本研究完成後,我們將確認核苷酸醣轉運蛋白SLC35A2在腫瘤組織的表現對神經母細胞瘤病人預後的重要性,了解SLC35A2的表現在神經母細胞瘤中對腫瘤惡性行為及細胞自噬的影響,以及其中的分子機制。藉由這樣的了解,希望未來可以進一步針對這個預後不好的腫瘤設計出新的治療策略或藥物,增進治療的成績、改善病人的預後。
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