https://scholars.lib.ntu.edu.tw/handle/123456789/79903
標題: | Noninvasive assessment of the viscoelasticity of peripheral arteries | 作者: | YIO-WHA SHAU Wang, Chung-Li JENG-YI SHIEH Hsu T.-C. |
公開日期: | 1999 | 卷: | 25 | 期: | 9 | 起(迄)頁: | 1377-1388 | 來源出版物: | Ultrasound in Medicine & Biology | 摘要: | Currently used methods of examining the mechanical properties of blood vessel walls are either indirect or invasive, or measure vessel diameter and pressure waveforms at different sites. We developed a noninvasive technique to assess the mechanical properties and viscoelasticity of peripheral arteries. The pressure-strain elastic modulus (Ep) and the viscoelastic properties (energy dissipation ratio, EDR) of the common carotid artery (CCA), brachial artery (BA), radial artery (RA) and dorsalis pedis artery (DPA) were determined by means of palpating pressure and diameter distension waveforms extracted from high-resolution ultrasonography. The methodology was validated in vitro using an elastic tube phantom, as well as in vivo. In vivo study in 10 healthy volunteers (mean age 22 y) showed that the pressure- diameter curves were nonlinear, with an inflection at about 85-90 mmHg, and routed clockwise with slight hysteresis. The CCA (n = 5) had a mean diameter of 6.74 mm and the pulsatile diameter distension was 12.2%. The Ep calculated at the CCA was 0.44 x 106 dyne/cm2 with an EDR of 7.18%. The BA, RA and DPA (n = 10) had mean diameters of 3.91 mm, 2.21 mm and 2.12 mm; arterial strains of 4.60%, 4.25% and 8.91%; mean Ep of 1.39, 1.45, 0.90 x 106 dyne/cm2; and mean EDRs of 6.34%, 6.15% and 5.60%, respectively. The method presented is relatively simple to implement clinically and has potential as a new diagnostic tool for detecting local vascular changes. |
URI: | http://ntur.lib.ntu.edu.tw//handle/246246/107066 | DOI: | 10.1016/S0301-5629(99)00097-6 | SDG/關鍵字: | adult; artery compliance; article; brachial artery; common carotid artery; female; human; human experiment; hysteresis; image analysis; image processing; intravascular ultrasound; male; normal human; priority journal; radial artery; viscoelasticity; Adult; Arteries; Blood Pressure; Brachial Artery; Carotid Artery, Common; Elasticity; Extremities; Female; Foot; Humans; Male; Phantoms, Imaging; Pulse; Radial Artery; Viscosity; Blood vessels; Elastic moduli; Energy dissipation; Hysteresis; Medical imaging; Noninvasive medical procedures; Viscoelasticity; Waveform analysis; High-resolution ultrasonography; Ultrasonic imaging |
顯示於: | 應用力學研究所 |
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