Non-invasive measurement of mechanical properties of peripheral arteries
Date Issued
2001-07-31
Date
2001-07-31
Author(s)
DOI
892314B002505M08
Abstract
A novel methodology was developed
for the detection of arterial mechanical
properties non-invasively using
high-resolution ultrasound. The vascular
wall motion is recorded simultaneously
with the pulsatile pressure, thus the
stress-strain relationship can be derived
accurately.
The subjects studied were divided into
three groups: young, diabetic patients and
their age-matched control. Postural change
was adopted to investigate the vascular
muscle tone and sympathetic response of
peripheral arteries. Results show that the
vessel distensibility at the dsalis pedis artery
(DPA) decrease substantially with age
(8.91±0.88% vs. 6.96±1.95%, p<0.01), the
corresponding arterial elastic modulus
increase (0.90±0.11vs.1.51±0.39 Mdyne/cm2,
p<0.01) and the energy dissipation ratio
(EDR) increase (5.60±1.29% vs.
8.08±1.61%). The arterial mechanical
properties of young group reacted more
effectively to the postural variation, which
suggested that the autonomic function in the
lower extremity would decay with age.
The diabetic patients have higher mean
arterial pressure than the control group, their
peripheral arterial distensibility decrease, the
pressure-diameter elastic modulus increase
and EDR increase notably (DPA: 8.08±
1.61% vs.11.51±2.07%). The peripheral
arteries in the lower extremity of DM patient
were significantly affected by the circulatory
diseases than the vessels in the upper trunk,
this signifies the lost or degeneration of
sympathetic tone in diabetic foot.
Subjects
Ultrasound
Peripheral Arteria
Viscoelasticity
Diabetic Mellitus
SDGs
Publisher
臺北市：國立臺灣大學應用力學研究所
Type
report
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